##plugins.themes.academic_pro.article.main##
Abstract
A study aimed to evaluate the effect of Salmonella Pullorum infection on vaccinal immunity against ND and AIV in a broiler. Before starting the study collected several samples from suspected infected flocks with S. Pullorum (OM988162.1), and identified by several biochemical test then molecular test PCR and confirmed isolates by sequencing. then take two hundred and fifty (Ross 308) Five groups of broiler chicks were formed. Each group has 50 chicks., as follow first group: infected with S. Pullorum and vaccinated against (NDV, AIV). Second group: infected with S. Pullorum and treated by (ciprofloxacin 10% 1ml / liter or 20 % 0,5 L for 7day and colistin 200million IU/0.5L for 7 days) also vaccinated against (NDV, AIV). Third group: infected with S. Pullorum and treated by (ciprofloxacin 10% 1ml/ liter or 20 % 0,5 L for 7day and colistin 200million IU/0.5L for 7 days) only. Fourth group: infected with S. Pollorum only as consider control positive. Five group: uninfected and unvaccinated as consider control negative. Antibodies titre (IgG and IFN-γ) against ND and AIV were significantly increased in G1 with the least histopathological changes in liver, kidney, bursa of fabricius, and thymus. G1 and G4 growth performance was significantly lower than that of treatment groups G2 and G3. Conclusion: S. Pullorum infection increased vaccinal immunity (IgG and IFN-γ) against Newcastle and influenza. Ciprofloxacin and colistin treatment improved body weight and weight gain
Keywords
##plugins.themes.academic_pro.article.details##
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
- Antunes, L. C., Arena, E. T., Menendez, A., Han, J., Ferreira, R. B.& Buckner, M. M. (2011). Impact of Salmonella infection on host hormone metabolism revealed by metabolomics. Infect. Immun., 79: 1759–1769. doi: 10.1128/IAI.01373-10.
- Brown, I.H.( 2010). Summary of avian influenza activity in Europe, Asia, and Africa,. Avian Dis., 54(1 Suppl):187-93.
- Caicai Chen, Jiayi Li, Hongxing Zhang, Yuanhong Xie, (2020 ). Effects of a probiotic on the growth performance, intestinal flora,and immune function of chicks infected with Salmonella pullorum. Poultry Science, 99:5316–5323.
- Couper, K. N., Blount, D. G. & Riley, E. M. (2008). IL-10: the master regulator of immunity to infection. J Immunol, 180, 5771-7.
- Endris, M., Taddesse, F. , Geloye, M. , Degefa T. & Jibat, T.( 2013). Sero and media culture prevalence of Salmonellosis in local and exotic chicken, Debre Zeit, Ethiopia. African Journal of Microbiology Research, 7(12): 1041-1044.
- Hamal, K. R., Burgess, S. C., Pevzner, I. Y.& Erf. G. F. (2006). Maternal antibody transfer from dams to their egg yolks, egg whites, and chicks in meat lines of chickens. Poult. Sci. 85:1364–1372
- Higgins, S. E., Higgins, J. P., Wolfenden, A. D., Henderson, S. N., Torres-Rodriguez, A. , Tellez, G.& Hargis. B. (2008). Evaluation of a Lactobacillus-based probiotic culture for the reduction of Salmonella enteritidis in neonatal broiler chicks. Poult. Sci. 87:27–31
- Kaiser, P., Stäheli, P. (2008). Avian cytokines and chemokines. In: Davison, F., Kaspers, B., Schat, K.A. (Eds.), Avian Immunology. Academic Press, London, pp. 203–222.
- KeDing, KeShang, Zu-Hua Yu, Chuan Yu. (2018). Recombinant-attenuated Salmonella Pullorum strain expressing the hemagglutinin-neuraminidase protein of Newcastle disease virus (NDV) protects chickens against NDV and Salmonella Pullorum challenge. Journal of Veterinary Science, 19(2): 232-241.
- Lambrecht, B., Gonze, M. , Meulemans, G. & van den Berg. T. P. ( 2004). Assessment of the cell-mediated immune response in chickens by detection of chicken interferon-γ in response to mitogen and recall Newcastle disease viral antigen stimulation. Avian Pathol. 33:343–350.
- Laxminarayan, R.& Heymann, D.L.(2012). Challenges of drug resistance in the developing world. BMJ 344, e1567.
- Lowenthal, J.W., Digby, M.R. & York. J.J. ( 1995). Production of interferon‐gamma by chicken T cells. J Interferon Cytokine Res., 15:933–938.
- Netsanet, B., Berihun, A. , Nigus, A. , Abreha T. & Shewit, K. (2012). Seroprevalence of Salmonella pullorum infection in local and exotic commercial chicken from Mekelle areas, northern Ethiopia Revista Electrónica de Veterinaria, 13(9): 1-15(.
- Nordin, M., Lorenz, T.& Campello, M. (2001).Biomechanics of tendons and ligaments. IN: Nordin M. Frankel VH (Eds). Basic biomechanics of the musculoskeletal system London, UK: Lippincott Williams & Wilkins 102-125.
- Ross,R.T.,Holtman,D.F.&Andgilfillan,R.F.(1955).TheeffectofSalmonellapulloruminfectiononaminoacidsofthechick.J.Bacteriol.,70,272-275.278 ,VOL.70
- Sick, C., Schneider, K. , Staeheli, P. & Weining, K.C. ( 2000). Novel chicken CXC and CC chemokines. Cytokine. 12:181–186.
- Suarez, D.L., & Schultz, C.S. (2000). Immunology of avian influenza virus: a review. Dev CompImmunol.24:269283.
- Sui, M., Yu, L. , Xie, Y. H. & Zhang.ri H. X. ( 2016). Study on tolerance characteristics of the gastrointestinal tract and cholesterol lowering effects of Lactobacillus plantarum Zhang-LL. Sci. Technology Food Industry 37:226–229.
- Swayne DE. (2020).Avian influenza. In: Foreign animal diseases. Boca Raton, FL: United States Animal Health Association; p. 137-46.
- Tang, Y., Foster, N., Jones, M.A., Barrow, P.A. (2018). Model of Persistent Salmonella Infection: Salmonella enterica Serovar Pullorum Modulates the ImmuneResponse of the Chicken from a Th17-Type Response towards a Th2-Type Response. Infect Immun. 86(