Morphological Changes In The Liver In Steatosis Induced By The Use Of Burdock Root (Arctium Lappa) Extract: An Experimental Study
DOI:
https://doi.org/10.62480/tjms.2025.vol50.pp48-51Keywords:
liver steatosis, fatty liver disease, Arctium lappaAbstract
The aim of the study was to investigate morphological changes in the liver during experimental steatosis and to evaluate the corrective effect of burdock root (Arctium lappa) extract. Steatosis was induced in laboratory animals using a high-fat diet combined with the hepatotoxic action of thioacetamide. Morphometric and histological examinations revealed pronounced fatty infiltration, ballooning degeneration of hepatocytes, inflammatory infiltration, and signs of early fibrosis. Administration of A. lappa extract led to a reduction in the degree of steatosis, decreased inflammation, and restoration of the lobular architecture of the liver. The findings indicate the promising potential of burdock root as a natural hepatoprotective agent.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
User Rights
Under the Creative Commons Attribution-NonCommercial 4.0 International (CC-BY-NC), the author (s) and users are free to share (copy, distribute and transmit the contribution).
Rights of Authors
Authors retain the following rights:
1. Copyright and other proprietary rights relating to the article, such as patent rights,
2. the right to use the substance of the article in future works, including lectures and books,
3. the right to reproduce the article for own purposes, provided the copies are not offered for sale,
4. the right to self-archive the article.
