Texas Journal of Medical Science

The first results of remote mammographic breast cancer screening in Surkhandarya region

M. S. Salomov, Sh. Sh. Khursandova, A. A. Kenzhaev — Sun, 03 Mar 2024 00:00:00 +0000

The widespread introduction of mammographic screening for early detection of breast cancer in the world has reduced the mortality rate of women from this disease in the general population by 20-30%. For many years, different standard mammographic screening methods have been used in the United States and many European countries, the principles of which are the same. It is common practice to standardize the X-ray mammography process and mammography characteristics in order to divide all healthy screened women into groups requiring different monitoring recommendations after the first mammogram. Viewing mammograms by two radiologists is considered recognized in the world to reduce the number of erroneous conclusions. In connection with the adoption of the law on medical examination of the population of the Republic of Uzbekistan, which provides for mammography for women after 45 years of age once a year, the question arises of standardizing this process in order to reduce breast cancer mortality in the regions of the Republic of Uzbekistan.

Skin diseases are a common problem among young adults

Xaydarova Shaxrizoda Husan qizi — Sun, 09 Mar 2025 00:00:00 +0000

Skin diseases are a major health problem affecting a high proportion of the population in India.[1] Skin diseases can place a heavy emotional and psychological burden on patients that may be far worse than the physical impact.[2] Increased consciousness especially among the youth of their body and beauty further aggravates their anxiety.[3] Many factors determine the pattern and prevalence of cutaneous diseases among the youth such as gender, race, personal hygiene, quality of skin care, environmental milieu and diet.[4] In some instances, patients appear to produce their skin lesions as an outlet for nervous tensions arising from interpersonal conflicts and/or unresolved emotional problems

Organizing Training Sessions For Submitting Health Test Requirements And Standards

Hamroqulov Rasul Abdusattorovich — Wed, 05 Mar 2025 00:00:00 +0000

In this article, health tests are used to determine the physical development and physical fitness of the population, and to form a habit of systematically performing physical exercises for a healthy lifestyle.

Comparative Characteristics Of Body Composition In Obesity Phenotypes

Sat, 15 Mar 2025 00:00:00 +0000

to study bioimpedance parameters of Uzbek women of childbearing age suffering from metabolically healthy and metabolically complicated obesity, to study their correlation with the degree of obesity and some biological markers

Clinical Pharmacological Approach To The Use Of Antiarrhythmic Drugs In Children

Kosimov Z.O. — Thu, 06 Mar 2025 00:00:00 +0000

The clinical pharmacological approach to the use of antiarrhythmic drugs in children is crucial for ensuring effective and safe treatment of cardiac arrhythmias. This article explores the classification, mechanisms of action, indications, contraindications, and potential adverse effects of commonly used antiarrhythmic agents in pediatric patients. Special attention is given to the pharmacokinetics and pharmacodynamics of these drugs in children, considering age-related differences in drug metabolism and response. The importance of individualized therapy, monitoring strategies, and recent advancements in pediatric cardiology are also discussed

Clinical Pharmacological Approach To The Use Of Hypolipidemic Drugs In The Treatment Of Atherosclerotic Disease

Sobirjonov I.T. — Thu, 13 Mar 2025 00:00:00 +0000

To evaluate the hypolipidemic effect, the impact on endothelial function, oxidative stress of pitavastatin at a dose of 4 mg in patients with dyslipidemia, arterial hypertension (AH) and chronic obstructive pulmonary disease (COPD) at baseline, in dynamics after 4 weeks and 12 months of treatment. The prospective study included 33 patients (mean age – 60 years) with hypertension, COPD and dyslipidemia. Laboratory examination consisted of determining the lipid spectrum, the level of lipid peroxidation products (LPO). In order to assess the tolerability of the prescribed therapy, creatinine, bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST) were studied

Clinical Pharmacological Approach To The Treatment Of Eclampsia In Pregnant Women With Antihypertensive Drugs

Usmonova F.T. — Thu, 13 Mar 2025 00:00:00 +0000

The review considers the possibilities of predicting preeclampsia (PE) and its complications, modern criteria for diagnosing hypertensive gestational disorders, as well as the tactics of their intensive therapy. Particular attention is paid to providing anesthetic support during operative delivery in patients with PE and its complications

Clinical Pharmacological Approach To Rational Drug Treatment Of Chronic Heart Failure

Bazarova A.M. — Tue, 11 Mar 2025 00:00:00 +0000

The clinical pharmacological approach to the rational drug treatment of chronic heart failure (CHF) focuses on optimizing therapeutic strategies to improve patient outcomes. This article examines the pharmacological classes of drugs used in CHF management, including angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, diuretics, aldosterone antagonists, and novel agents. The mechanisms of action, indications, contraindications, and potential adverse effects of these drugs are analyzed. Special emphasis is placed on the importance of individualized treatment, drug interactions, and evidence-based guidelines. Advances in pharmacotherapy and personalized medicine approaches for enhancing the efficacy and safety of CHF treatment are also discussed.

Clinical Pharmacology Of Metabolism-Activating And Correcting Drugs

Urinboev L.X. — Wed, 12 Mar 2025 00:00:00 +0000

The article covers the issues of drug metabolism in patients with various liver diseases, presents pathophysiological mechanisms of impaired biotransformation of substances depending on the severity of hepatocyte damage, names the causes of drug interactions of pharmacological agents, leading to an undesirable increase in the concentration of the drug in the blood, strengthening and prolongation of the therapeutic effect with an increased risk of side effects

Clinical Pharmacological Approach To The Treatment Of Infectious Diseases With Antiviral Drugs

Abubakirov X.Y. — Fri, 14 Mar 2025 00:00:00 +0000

The clinical efficacy and safety of riamilovir were assessed based on the results of a study of 150 patients in three compared groups, 50 patients in each. Patients received etiotropic antiviral therapy with riamilovir, 1 capsule (250 mg) 3 times a day for 5 days in the first group, in the second group patients received riamilovir in the “off label” regimen, 1 capsule (250 mg) 5 times a day for 5 days, and the third group consisted of 50 patients who received only pathogenetic treatment. The etiotropic antiviral drug riamilovir demonstrated clinical efficacy when used in both treatment regimens in patients with ARVI and a good safety profile

Clinical Pharmacological Approach To The Treatment Of Infectious Diseases With Antiviral Drugs

Abubakirov X.Y. — Sat, 15 Mar 2025 00:00:00 +0000

Clinical Pharmacology Of Immunocorrector Drugs

Odiljonova A.B. — Fri, 14 Mar 2025 00:00:00 +0000

The concept, strategy and principles of immunocorrection and immunomodulatory therapy, pharmacological and immunobiological characteristics, mechanisms of action of immunomodulators of various natures, indications for their use are presented

Clinical Pharmacological Approach To The Use Of Antibacterial Therapy In Older People

Rasulov B.A. — Fri, 14 Mar 2025 00:00:00 +0000

The clinical pharmacological approach to antibacterial therapy in older people is crucial for ensuring effective treatment while minimizing adverse effects and resistance development. This article explores age-related physiological changes that influence drug pharmacokinetics and pharmacodynamics, including altered absorption, distribution, metabolism, and excretion. The selection of appropriate antibacterial agents, dose adjustments, drug interactions, and the risks of polypharmacy in elderly patients are analyzed. Additionally, strategies for optimizing therapy to reduce antibiotic resistance and improve patient outcomes are discussed, along with recent advancements in geriatric antimicrobial stewardship

Clinical Pharmacological Approach To The Drug Treatment Of Arthritis, Arthralgia And Back Pain Syndromes

Akhmedov B.U. — Fri, 14 Mar 2025 00:00:00 +0000

The article is devoted to one of the most common rheumatic diseases — juvenile arthritis (JA). The main issues of epidemiology, classification, pathogenesis are considered, in more detail — the clinical picture of different variants of the course of JA, diagnostics and differential diagnosis. The treatment section describes the drugs used in JA, and presents an algorithm for differentiated treatment of the disease. Approaches to biological therapy, conditions for prescribing and management of patients receiving genetically engineered biological drugs are described separately.

Ascertaining The Health Consequences of Delayed Menstrual Period Among Students of Tertiary Institutions on The Family In South-South Nigeria

Thu, 20 Mar 2025 00:00:00 +0000

Regular monthly menstrual period is a natural process that occur in female from pubertal stage to certain age before menopause. Delayed menstrual period among female students may pose different health consequences, indicating an underlying cause and this may have impact on both students and their immediate family. These health consequences may hinder students’ academic performance. The aim of this study is Ascertaining the Health Consequences of Delayed Menstrual Period Among Students of Tertiary Institutions on the Family in South-South Nigeria. This was a descriptive study involving 250 female students in tertiary institutions who were within the age of 18 to 47 years. A well-structured questionnaire was administered to participants. Each participant had one questionnaire to fill appropriately and independently after instructions were given to them by the Research Assistants. The study lasted for a period of 3 months (April to June, 2024). Data was analyzed with SPSS version 26 and P value < 0.05 was considered significant. Exclusion criteria were those females who are not student. Inclusion criteria are female students that have attained menarche. Results from the study revealed some of the health consequences of delayed menstrual period observed emanated from hormonal imbalance, stress, pregnancy, nutritional disorders, underlying reproductive issues and being on certain medications. Again, 85% of the students had abortion due to unwanted pregnancy, 65% had PID, 25% ectopic pregnancy, 78% had anaemia from bleeding, 65% experienced pains, 55% experienced sycopal attacks, 75% had irregular menstrual period, 85% had weight gain, and 67% experienced body weakness