Texas Journal of Medical Science
type: channel
description: Texas Journal of Medical Science provides the opportunity to the authors to publish their original research articles in Medical Sciences and allied field. Frequency of Publication: Monthly Acceptance Notification: 45 Days ISSN (Online): 2770-2936 doi Prefix: 10.62480
publisher: Zien Journals
language: en
publication name: Texas Journal of Medical Science
issn: 2770-2936
copyright: User Rights Under the Creative Commons Attribution-NonCommercial 4.0 International (CC-BY-NC), the author (s) and users are free to share (copy, distribute and transmit the contribution). Rights of Authors Authors retain the following rights: 1. Copyright and other proprietary rights relating to the article, such as patent rights, 2. the right to use the substance of the article in future works, including lectures and books, 3. the right to reproduce the article for own purposes, provided the copies are not offered for sale, 4. the right to self-archive the article.
items: Endocrine and Genetic Mechanisms of the Influence of Subclinical Thyroid Dysfunction on Women’s Reproductive Health
items: The Significance Of Physical Culture And Sports And Their Integration Into The Daily Life Of Students
items: Comparative Efficacy Of Pharmacotherapy And Combined Psycho-Pharmacotherapy For Correction Of Psychoemotional, Cognitive And Immunological Disorders In Post-Covid Syndrome Among Young Adults
items: Among Young People And Measures For Its Prevention The Increasing Prevalence Of Arterial Hypertension
items: Dynamics Of Changes In Natriuretic Hormone During Immobilization Stress
items: Modern approaches to the diagnosis and treatment of caries in therapeutic dentistry
items: Problems And Solutions Of Developing Life Skills Of A Healthy Lifestyle At All Levels Of The Population
items: Detection Of Birth Defects Through Early Perinatal Screening: Experience Of Developing Countries
items: Myocardial Dystrophy In Chronic Obstructive Pulmonary Disease: Mechanisms Of Development, Early Markers, And Treatment Approaches
items: The Role of Comorbidities in the Development of Bronchopulmonary Diseases in Military Personnel
items: POST-COVID Lipid Profile Alterations In Stage 3 Chronic Kidney Disease Patients
items: Prevalence Of The Ppargc1a Gene Gly482ser Polymorphism In Women With Obesity
items: Changes In Biochemical And Cytokine Markers Of The Liver In The Acute Period Of Combined Facial Trauma
items: Correlation Of The Functional State Of The Liver And The Severity Of Patients In The Complex Treatment Of Combined Facial Bone Trauma
items: Bone and bone-substituting materials in plastic surgery of oroantral perforations of the maxillary sinus.
items: Dynamics of Clinical, Laboratory, and Morphostructural Parameters in Patients with Infected Pancreatic Necrosis Associated with Diabetes Mellitus
items: Morphological Characteristics, Histogenesis, And Differential Diagnosis Principles of Cardiac Myxoma
items: Echocardiography: Current Problems and Prospects in Modern Diagnostics
items: Associate,Dosent Tashkent State University of Economics, Department of Uzbek and Russian Languages
items: Headache As A Manifestation Of Paranasal Sinus Diseases: The Significance Of Plain Radiography
items: Comparative Analysis Of Quality-Of-Life Indicators After Total And Subtotal Thyroidectomy
items: The Importance Of Proteins And Protein-Containing Medicinal Products In Medicine
items: Sovremennye Cojnye Meniteli I Kananeinjenernye Construction And Reconstruction Of Cojnyx Defects In The Maxillofacial Area
items: Supporting clinical decisions through artificial intelligencebased biomarker analysis and finite material modeling for non-invasive maxillofacial bone regeneration using BTCP/PLLA scaffolds
items: Algorithms for extracting the QRS complex from the ECG
items: Reproductive Health Problems in Women
items: Analysis of the relationship between hemodynamic parameters and markers of renal dysfunction, Klotho protein, vitamin D, and parathyroid hormone in hypertension
items: Brain Neuroplasticity in Students Under Conditions of Intensive Learning: Molecular and Cellular Mechanisms
items: Laparoscopy In The Diagnosis Of Acute Surgical Diseases Of The Abdominal Organs
items: Clinical Efficacy Of Diagnostic Laparoscopy In Abdominal Trauma

Endocrine and Genetic Mechanisms of the Influence of Subclinical Thyroid Dysfunction on Women’s Reproductive Health
type: item
description: Subclinical thyroid dysfunction is one of the most common endocrine disorders among women of reproductive age and represents an important medical and social problem due to its impact on fertility, menstrual function, pregnancy outcomes, and hormonal balance. Subclinical hypothyroidism and subclinical hyperthyroidism are characterized by altered thyroid-stimulating hormone levels with normal circulating thyroid hormone concentrations. Despite the absence of pronounced clinical manifestations, these conditions may significantly affect reproductive health through complex endocrine and genetic mechanisms. Thyroid hormones regulate ovarian function, folliculogenesis, ovulation, implantation, and placental development. Disturbances in thyroid homeostasis can lead to menstrual irregularities, infertility, miscarriage, polycystic ovary syndrome, and adverse obstetric outcomes. In recent years, increasing attention has been paid to the genetic and molecular mechanisms underlying the relationship between thyroid dysfunction and reproductive disorders. Genetic polymorphisms involving thyroid hormone receptors, deiodinases, autoimmune susceptibility genes, and reproductive hormone receptors may contribute to impaired fertility and hormonal imbalance in affected women. This article reviews current scientific evidence regarding the endocrine and genetic pathways linking subclinical thyroid dysfunction with female reproductive health and highlights the importance of early diagnosis and personalized therapeutic strategies.
subject: Articles
  topic: section
subject: subclinical thyroid dysfunction
  topic: keywords
subject: reproductive health
  topic: keywords
subject: infertility
  topic: keywords
creator: Zokirova D.D
creator: Yusupova Sh.Q
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-22
publication date: 2026-05-22
starting page: 35
ending page: 38
doi: 10.62480/tjms.2026.vol56.pp35-38

The Significance Of Physical Culture And Sports And Their Integration Into The Daily Life Of Students
type: item
description: The article examines the importance of physical culture and sport in the life of modern university students and analyzes the conditions required for their effective integration into students’ daily routines. It is argued that physical culture within higher education should be understood not as an isolated academic subject or occasional exercise, but as a substantial component of personal culture that supports health preservation, psychological resilience, self-regulation, social inclusion, and academic performance. Drawing on current international guidelines and systematic reviews, the paper shows that regular physical activity is associated with reduced risk of chronic noncommunicable diseases, improved mental well-being, lower levels of anxiety, depressive symptoms, and stress, as well as with several positive educational and behavioral outcomes
subject: Articles
  topic: section
subject: physical culture
  topic: keywords
subject: sport
  topic: keywords
subject: students
  topic: keywords
subject: daily life
  topic: keywords
creator: Akbarova Gulbakhor Tokhirovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-16
publication date: 2026-05-16
starting page: 31
ending page: 34
doi: 10.62480/tjms.2026.vol56.pp31-34

Comparative Efficacy Of Pharmacotherapy And Combined Psycho-Pharmacotherapy For Correction Of Psychoemotional, Cognitive And Immunological Disorders In Post-Covid Syndrome Among Young Adults
type: item
description: Post-COVID syndrome (PCS) in young adults is characterized by persistent psychoemotional disturbances, cognitive dysfunction, and immune dysregulation
subject: Articles
  topic: section
subject: post-COVID syndrome
  topic: keywords
subject: young adults
  topic: keywords
subject: cognitive-behavioral therapy
  topic: keywords
creator: Tuychiev Sh.T
creator: Abdullaeva V.K
creator: Nabieva U.P
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-19
publication date: 2026-05-19
starting page: 25
ending page: 30
doi: 10.62480/tjms.2026.vol56.pp25-30

Among Young People And Measures For Its Prevention The Increasing Prevalence Of Arterial Hypertension
type: item
description: Arterial hypertension has become an increasingly prevalent health concern among young people worldwide. This study examines the growing incidence of hypertension in youth, its etiological factors, pathophysiological mechanisms, and preventive strategies. Major risk factors include unhealthy dietary habits, sedentary lifestyle, chronic stress, obesity, hereditary predisposition, and excessive consumption of energy drinks. The article highlights the importance of early diagnosis, regular blood pressure monitoring, and implementation of preventive interventions such as healthy nutrition, physical activity, stress management, and sleep hygiene. Effective prevention and early management of hypertension in young populations may significantly reduce future cardiovascular morbidity and mortality
subject: Articles
  topic: section
subject: arterial hypertension
  topic: keywords
subject: youth health
  topic: keywords
subject: cardiovascular risk factors
  topic: keywords
creator: S.G. Usmonova
creator: Ulmasov Ziyodillo
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-09
publication date: 2026-05-09
starting page: 22
ending page: 24
doi: 10.62480/tjms.2026.vol56.pp22-24

Dynamics Of Changes In Natriuretic Hormone During Immobilization Stress
type: item
description: This literature review examines in detail the effects of natriuretic hormones during immobilization stress and the dynamics of their changes. It also provides information on the types of natriuretic hormones and their influence on the activity of other hormones. Experiments conducted on this topic and their results are described. The findings show that significant changes in natriuretic hormone secretion occur at the early stages of immobilization stress, and this process is closely associated with cardiac activity and stress hormones. Additionally, the activation of the neuroendocrine system and the heart’s endocrine responses under stress were assessed
subject: Articles
  topic: section
subject: Blood pressure
  topic: keywords
subject: cortisol
  topic: keywords
subject: hypothalamic-pituitary-adrenal system
  topic: keywords
subject: renin-angiotensin-aldosterone
  topic: keywords
creator: Nasirillayeva O.B
creator: Toshtemirova P.Z
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-17
publication date: 2026-04-17
starting page: 30
ending page: 35
doi: 10.62480/tjms.2026.vol55.pp30-35

Modern approaches to the diagnosis and treatment of caries in therapeutic dentistry
type: item
description: Dental caries remains one of the most common dental pathologies worldwide. Despite the development of preventive measures and improved treatment methods, the prevalence of the disease remains high among various age groups. Modern therapeutic dentistry focuses not only on eliminating defects in hard dental tissues but also on early diagnosis, minimally invasive treatment, and recurrence prevention. This article discusses modern methods of diagnosis, treatment, and prevention of dental caries
subject: Articles
  topic: section
subject: therapeutic dentistry
  topic: keywords
subject: caries
  topic: keywords
subject: remineralization
  topic: keywords
creator: Azimov Saidabror Kayumzhon Ugli
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-09
publication date: 2026-05-09
starting page: 19
ending page: 21
doi: 10.62480/tjms.2026.vol56.pp19-21

Problems And Solutions Of Developing Life Skills Of A Healthy Lifestyle At All Levels Of The Population
type: item
description: One of the main tasks of the society is to popularize knowledge about organizing a healthy lifestyle among the people. The article is devoted to the problem of health and the formation of a healthy lifestyle
subject: Articles
  topic: section
subject: Lifestyle
  topic: keywords
subject: solution
  topic: keywords
subject: method
  topic: keywords
subject: health
  topic: keywords
creator: Djuraeva Gulnora Abdukhalilovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-09
publication date: 2026-05-09
starting page: 16
ending page: 18
doi: 10.62480/tjms.2026.vol56.pp16-18

Detection Of Birth Defects Through Early Perinatal Screening: Experience Of Developing Countries
type: item
description: This article provides a scientific analysis of the importance of early perinatal screening in the detection of birth defects, the level of its application in developing countries, and systemic problems. The study examined the effectiveness of prenatal diagnostic methods, infrastructural and personnel constraints in the healthcare system, as well as socio-cultural factors. In addition, the possibilities of modernizing the screening system based on artificial intelligence and digital technologies were assessed. The results show that by improving the screening system, it is possible to significantly improve maternal and child health indicators.
subject: Articles
  topic: section
subject: Perinatal screening
  topic: keywords
subject: birth defects
  topic: keywords
subject: prenatal diagnosis
  topic: keywords
creator: Djalilova Gulnoza Abduhamidovna
creator: Ahadjanova Shoira Halilovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-07
publication date: 2026-05-07
starting page: 11
ending page: 15
doi: 10.62480/tjms.2026.vol56.pp11-15

Myocardial Dystrophy In Chronic Obstructive Pulmonary Disease: Mechanisms Of Development, Early Markers, And Treatment Approaches
type: item
description: This article examines the relationship between chronic obstructive pulmonary disease (COPD) and myocardial dystrophy, focusing on pathophysiological mechanisms, diagnostic approaches, and therapeutic strategies. A total of 120 COPD patients were evaluated for myocardial dysfunction using echocardiography, cardiac biomarkers (NT-proBNP, troponin I, CK-MB), and inflammatory markers (IL6, TNF-α, CRP). The results demonstrated that myocardial dystrophy is present in 68.3% of COPD patients, with severity correlating with disease stage. Hypoxia-driven oxidative stress and systemic inflammation were identified as the primary mechanisms. Combined bronchodilator therapy supplemented with cardioprotective agents (trimetazidine 35 mg twice daily) significantly improved both pulmonary and cardiac functional parameters.
subject: Articles
  topic: section
subject: chronic obstructive pulmonary disease
  topic: keywords
subject: myocardial dystrophy
  topic: keywords
subject: cor pulmonale
  topic: keywords
creator: Nurullayev B.A
creator: Turakulov R.I
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-07
publication date: 2026-05-07
starting page: 8
ending page: 10
doi: 10.62480/tjms.2026.vol56.pp8-10

The Role of Comorbidities in the Development of Bronchopulmonary Diseases in Military Personnel
type: item
description: This study investigates the role of comorbidities in the course of bronchopulmonary diseases among military personnel. Comorbid conditions were identified in 59.3% of patients. The most common were gastrointestinal diseases (37.7%), cardiovascular diseases (10.6%), kidney diseases (7.7%), and diabetes mellitus (3.3%). Cardiovascular diseases (OR=19.6; p
subject: Articles
  topic: section
subject: bronchopulmonary diseases
  topic: keywords
subject: bronchopulmonary diseasesmilitary personnel
  topic: keywords
subject: pneumonia
  topic: keywords
creator: Jakbarova Moxida Abduqaxxor qizi
creator: Shonazarov A. A.
creator: Suyunov O.O.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 1
ending page: 3
doi: 10.62480/tjms.2026.vol56.pp1-3

POST-COVID Lipid Profile Alterations In Stage 3 Chronic Kidney Disease Patients
type: item
description: The study evaluated changes in renal functional status in patients with stage 3 chronic kidney disease (CKD) who had previously experienced COVID-19 infection. A total of 131 patients were included in the study: • Group 1 — CKD stage 3 (n=70); • Group 2 — CKD stage 3 + COVID-19 (n=61). For each patient, the lipid profile was evaluated, including: Total cholesterol (TC, mmol/L), Triglycerides (TG, mmol/L), Low-density lipoprotein cholesterol (LDL-C, mmol/L), High-density lipoprotein cholesterol (HDL-C, mmol/L) Laboratory measurements were performed at 1 month and 3 months. Data are presented as mean ± SEM. Statistical analysis was conducted using Student’s t-test or appropriate parametric tests. Significant changes over the 3-month period were indicated with an asterisk (*), p
subject: Articles
  topic: section
subject: Chronic kidney disease
  topic: keywords
subject: COVID-19
  topic: keywords
subject: lipid profile
  topic: keywords
subject: total cholesterol
  topic: keywords
creator: Azim A. Djabbarov
creator: Dilrukh Kh. Madazimova
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 1
ending page: 4
doi: 10.62480/tjms.2026.vol56.pp1-4

Prevalence Of The Ppargc1a Gene Gly482ser Polymorphism In Women With Obesity
type: item
description: In recent years, according to leading scientists, a hereditary predisposition to obesity has been identified. Various mutations that significantly affect energy metabolism and adipose tissue proliferation can lead to the development of obesity, but in most patients they are not detected. This article presents the results of research on proving the prevalence of the PPARGC1A gene polymorphism in Uzbek women of childbearing age with obesity and creating the necessary conditions for determining the potential goals of drug therapy and developing personalized effective approaches to the diagnosis, treatment, and prevention of obesity.
subject: Articles
  topic: section
subject: women of childbearing age
  topic: keywords
subject: metabolic healthy obesity
  topic: keywords
creator: Ra’no K.Dadabaeva
creator: Sabohat S.Turakhozhaeva
creator: Feruza M.Nuriddinova
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-25
publication date: 2026-04-25
starting page: 56
ending page: 59
doi: 10.62480/tjms.2026.vol55.pp51-54

Changes In Biochemical And Cytokine Markers Of The Liver In The Acute Period Of Combined Facial Trauma
type: item
description: This article presents the results of an assessment of the functional state of the liver in patients with concomitant facial bone injuries. The study included 58 patients treated at the Andijan branch of the Russian Scientific Center for Emergency Medicine. Blood biochemical parameters reflecting inflammatory activity, protein-synthetic function of the liver, and the degree of cytolysis ( procalcitonin , total protein, albumin, ALT , and AST ) were assessed dynamically from admission to the seventh day. It was found that in the first hours after injury, a pronounced activation of the systemic inflammatory response and cytolytic syndrome is observed: a significant increase in procalcitonin , increased transaminase activity, and a decrease in protein fractions. By the fifth and seventh days, these parameters gradually normalize, indicating the restoration of metabolic liver function and the effectiveness of the therapy
subject: Articles
  topic: section
subject: combined injury
  topic: keywords
subject: maxillofacial region
  topic: keywords
subject: liver
  topic: keywords
creator: Boimurodov Shukhrat Abdujalilovich
creator: Nazhmiddinov Bokhodirzhon Bakhritdin ugli
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-26
publication date: 2026-03-26
starting page: 27
ending page: 30
doi: 10.62480/tjms.2026.vol54.pp27-30

Correlation Of The Functional State Of The Liver And The Severity Of Patients In The Complex Treatment Of Combined Facial Bone Trauma
type: item
description: The study comprehensively assessed the relationship between the severity of patients' general condition and liver function in patients with concomitant facial bone injuries. Biochemical and oxidative parameters were analyzed in 122 patients using clinical data, international severity assessment scales (ISS, GCS, PTS, PELOD), and laboratory test results. It was found that the severity of systemic inflammation and cytolysis, decreased protein-synthetic function of the liver, and impaired coagulation status correlated with the severity of traumatic injury. Patients receiving hepatoprotective therapy demonstrated more favorable dynamics of these parameters and more rapid clinical improvement. The obtained data confirm the significance of liver markers as prognostic criteria and emphasize the role of liver function correction in the comprehensive treatment of concomitant facial bone injuries
subject: Articles
  topic: section
subject: combined trauma
  topic: keywords
subject: maxillofacial injuries
  topic: keywords
creator: Nazhmiddinov Bokhodirzhon Bakhritdin ugli
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-26
publication date: 2026-03-26
starting page: 22
ending page: 26
doi: 10.62480/tjms.2026.vol54.pp22-26

Bone and bone-substituting materials in plastic surgery of oroantral perforations of the maxillary sinus.
type: item
description: Oroantral perforations (OAP) and fistulas are common complications of maxillary tooth extraction and lateral alveolar surgery. Soft tissue closure of the defect does not always ensure restoration of bone volume, which is important for subsequent implant rehabilitation. The aim of this review was to analyze the use of bone and bone-substituting materials in OAP repair, taking into account morphological healing mechanisms and postoperative rehabilitation. An analysis of domestic and international publications on the use of autogenous bone grafts, allogeneic and xenogeneic osteoplastic materials, collagen membranes, and combined composites for the closure of maxillary sinus floor defects was conducted. It was shown that the use of bone or bonesubstituting materials helps maintain alveolar bone height, improve the quality of the regenerated bone, and promote the formation of a complete bone structure, which is morphologically associated with accelerated osteoconduction and angiogenesis. The choice of material determines the rehabilitation strategy and the timing of subsequent implantation
subject: Articles
  topic: section
subject: oroantral perforation
  topic: keywords
subject: oroantral fistula
  topic: keywords
subject: bone grafting
  topic: keywords
creator: Ruzibayev Dilshod Ro’zimetovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-28
publication date: 2026-04-28
starting page: 51
ending page: 55
doi: 10.62480/tjms.2026.vol55.pp51-55

Dynamics of Clinical, Laboratory, and Morphostructural Parameters in Patients with Infected Pancreatic Necrosis Associated with Diabetes Mellitus
type: item
description: In this article, the authors analyze the dynamics of clinical, laboratory, and morphostructural parameters in patients with infected pancreatic necrosis (IPN) associated with diabetes mellitus (DM). Clinical studies were conducted in 62 patients with IPN and concomitant DM. The significance of clinical signs, laboratory parameters, instrumental diagnostic methods, and morphostructural indicators in patients with IPN associated with DM was evaluated. Overall, the authors conclude that a comprehensive assessment of clinical, laboratory, and morphostructural changes in patients with IPN and concomitant DM is accompanied by an increasing systemic inflammatory response, pronounced organ dysfunction, and progression of destructive foci during the first 1-3 days of the disease, followed by partial stabilization of the patients' condition by the 10th day as a result of ongoing comprehensive treatment. The study demonstrated that conventional therapeutic approaches do not ensure timely prevention of disease progression in patients with IPN associated with DM
subject: Articles
  topic: section
subject: infected pancreatic necrosis
  topic: keywords
subject: diabetes mellitus
  topic: keywords
subject: clinical
  topic: keywords
creator: Kasimov N.A
creator: Khakimov D.M
creator: Khodzhimatov G.M
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-18
publication date: 2026-04-18
starting page: 41
ending page: 50
doi: 10.62480/tjms.2026.vol55.pp41-50

Morphological Characteristics, Histogenesis, And Differential Diagnosis Principles of Cardiac Myxoma
type: item
description: To analyze the pathomorphological and immunohistochemical characteristics, as well as modern aspects of the histogenesis of cardiac myxoma, and to systematize the criteria for differential diagnosis with other intracardiac formations.
subject: Articles
  topic: section
subject: cardiac myxoma
  topic: keywords
subject: pathomorphology
  topic: keywords
subject: immunohistochemistry
  topic: keywords
subject: histogenesis
  topic: keywords
creator: Rashidova Shaxlo O'rmonovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-15
publication date: 2026-04-15
starting page: 38
ending page: 40
doi: 10.62480/tjms.2026.vol55.pp38-40

Echocardiography: Current Problems and Prospects in Modern Diagnostics
type: item
description: This article analyzes modern problems in the practice of echocardiography (EchoCG), which is the primary method in the non-invasive diagnosis of cardiovascular diseases. The dependence of image quality on the patient's constitution, subjectivity in measurements (human factor), as well as issues of standardization of new technologies such as 3D EchoCG and Speckle Tracking are highlighted. The role and prospects of artificial intelligence (AI) technologies in overcoming these problems are evaluated.
subject: Articles
  topic: section
subject: echocardiography
  topic: keywords
subject: cardiovascular diseases
  topic: keywords
subject: ultrasound diagnostics
  topic: keywords
creator: Rashidova Sh.U
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-18
publication date: 2026-04-18
starting page: 36
ending page: 37
doi: 10.62480/tjms.2026.vol55.pp36-37

Associate,Dosent Tashkent State University of Economics, Department of Uzbek and Russian Languages
type: item
description: Nasal breathing disorders are increasingly recognized as serious health concerns in the pediatric population. Recent research points to a robust connection between compromised nasal airflow and a variety of cognitive deficits in children. Persistent mouth breathing associated with nasal obstruction often results in altered craniofacial development and impacts sleep quality, which in turn can disrupt optimal brain maturation and neurocognitive functioning. This paper discusses the importance of monitoring cognitive functions in children affected by nasal breathing disorders, the neurobiological mechanisms linking respiratory impairment and cognitive deficits, available assessment methods, and evidence-based interventions. Special attention is given to the challenges in early detection, the role of multidisciplinary collaboration, and the implications for long-term developmental and academic outcomes.
subject: Articles
  topic: section
subject: nasal breathing disorders
  topic: keywords
subject: cognitive monitoring
  topic: keywords
subject: pediatric cognition
  topic: keywords
creator: Madjidova Yakutxon Nabievna
creator: Rajabova Khursandoy Rustamjon kizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-09
publication date: 2026-04-09
starting page: 27
ending page: 29
doi: 10.62480/tjms.2026.vol55.pp27-29

Headache As A Manifestation Of Paranasal Sinus Diseases: The Significance Of Plain Radiography
type: item
description: The prevalence of inflammatory diseases of the paranasal sinuses (PNS) remains consistently high, despite the introduction of modern diagnostic and treatment methods. This pathology occupies a significant place in the structure of outpatient visits to otorhinolaryngologists. In several regions, a particularly high incidence of sinusitis is observed; this is attributed to adverse environmental conditions, exposure to industrial factors, and the development of secondary immunodeficiency states within the population
subject: Articles
  topic: section
subject: Sinus Inflammation
  topic: keywords
subject: methods
  topic: keywords
subject: development
  topic: keywords
creator: Karimova Z.Kh
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-13
publication date: 2026-04-13
starting page: 21
ending page: 26
doi: 10.62480/tjms.2026.vol55.pp21-26

Comparative Analysis Of Quality-Of-Life Indicators After Total And Subtotal Thyroidectomy
type: item
description: Surgical treatment of thyroid diseases remains one of the main therapeutic approaches, while the choice of surgical extent (total or subtotal thyroidectomy) influences postoperative outcomes and patients’ quality of life. The aim of this study was to perform a comparative analysis of quality of life indicators following total and subtotal thyroidectomy. A prospective study involving 140 patients was conducted. Quality of life was assessed using the ThyPRO questionnaire. No statistically significant differences in the overall quality of life between the groups were identified (p>0.05); however, symptoms of hypothyroidism were more frequently observed after total thyroidectomy, whereas anxiety related to the risk of recurrence was more common after subtotal thyroidectomy. The incidence of hypoparathyroidism reached up to 22%, and transient recurrent laryngeal nerve paresis was observed in approximately 6.5% of cases. The obtained data confirm the comparability of these surgical methods despite differences in certain clinical aspects.
subject: Articles
  topic: section
subject: Thyroidectomy
  topic: keywords
subject: thyroid gland
  topic: keywords
subject: quality of life
  topic: keywords
subject: hypothyroidism
  topic: keywords
creator: Madvalieva Khushnoza Mansurzhonovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-10
publication date: 2026-04-10
starting page: 17
ending page: 20
doi: 10.62480/tjms.2026.vol55.pp17-20

The Importance Of Proteins And Protein-Containing Medicinal Products In Medicine
type: item
description: This article analyzes the biological and physiological significance of proteins, their main functions in the human body, as well as protein-based drugs and their fields of application in medicine. Proteins are the principal structural components of every living cell and play an essential role in metabolism, immune defense, enzymatic processes, and the maintenance of cellular integrity. The article also provides a broad overview of pathological conditions associated with proteins and the medical need for protein substances in clinical practice. It serves to strengthen theoretical knowledge and foster clinical thinking among students studying in the field of medicine
subject: Articles
  topic: section
subject: proteins
  topic: keywords
subject: protein-based preparations
  topic: keywords
subject: protein-based preparationsenzymes
  topic: keywords
creator: S.G. Usmonova
creator: Abdullajonova Zilola Alisher qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-08
publication date: 2026-04-08
starting page: 13
ending page: 16
doi: 10.62480/tjms.2026.vol55.pp13-16

Sovremennye Cojnye Meniteli I Kananeinjenernye Construction And Reconstruction Of Cojnyx Defects In The Maxillofacial Area
type: item
description: Restoration of the jaw defect in the maxillofacial region remains one of the most common types of reconstructive surgery due to the combination of high functional and aesthetic requirements. Traditional methods ( autodermoplasty , loskutnye operatsii) have a limited volume of donor tissue, risk of donor morbidity and expressed rubtsevaniem. Development of kojnyx zameniteley and tissue engineering construction (TIK) has opened up new possibilities for the regeneration of kojnyx cover skins, including the use of biopolymer matrices, cellular transplants, mesenchymal stem cells, and also technological 3Dbioprinting
subject: Articles
  topic: section
subject: skin replacement
  topic: keywords
subject: tissue engineering
  topic: keywords
subject: dermal equivalent
  topic: keywords
creator: Ruzibaev Dilshad Ruzimetovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-06
publication date: 2026-04-06
starting page: 7
ending page: 12
doi: 10.62480/tjms.2026.vol55.pp7-12

Supporting clinical decisions through artificial intelligencebased biomarker analysis and finite material modeling for non-invasive maxillofacial bone regeneration using BTCP/PLLA scaffolds
type: item
description: Maxillofacial bone regeneration remains a critical challenge in reconstructive surgery, where the integration of bioresorbable scaffolds such as B-TCP/PLLA (beta-tricalcium phosphate/poly-L-lactic acid) has shown promising osteoconductive and osteoinductive properties. In this study, we developed a comprehensive clinical decision support framework that combines finite element modeling (FEM) and machine learning-driven biomarker analysis to evaluate bone healing in patients treated with B-TCP/PLLA scaffolds. Quantitative biomarkers, including alkaline phosphatase (ALP), vascular endothelial growth factor (VEGF), and runt-related transcription factor 2 (Runx2), were collected at multiple postoperative intervals and processed using supervised learning algorithms such as Random Forest and Support Vector Machine (SVM). Our FEM simulations provided insight into stress distribution and scaffold integration, supporting the prediction of ossification patterns. Results show a strong correlation between computational stress models and biomarker expression levels, with the predictive model achieving an AUC of 0.91, precision of 0.88, and recall of 0.85. These findings underscore the potential of combining biomechanical modeling with molecular profiling to enhance postoperative monitoring and early prediction of bone regeneration outcomes. The proposed system offers a novel, data-driven approach for personalized treatment planning and real-time clinical support, contributing to the development of next-generation AIassisted healthcare tools in maxillofacial surgery.
subject: Articles
  topic: section
subject: Maxillofacial implants
  topic: keywords
subject: biomaterials
  topic: keywords
subject: reconstructive surgery
  topic: keywords
creator: Boymuradov Sh.A
creator: Mamanazarov A.N.
creator: Matchanov B.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-04-06
publication date: 2026-04-06
starting page: 1
ending page: 6
doi: 10.62480/tjms.2026.vol54.pp1-6

Algorithms for extracting the QRS complex from the ECG
type: item
description: ECG is a diagnostic signal recorded on the patient's body at standard electrode locations, which reflects the electrical activity of the heart muscle. One of the main features of the ECG is a pulse waveform called the QRS complex. This complex corresponds to the time of depolarization of the heart ventricles and is of important diagnostic importance.
subject: Articles
  topic: section
subject: QRS complex
  topic: keywords
subject: QRS complexPan-Tompkins algorithm
  topic: keywords
subject: High-pass filter
  topic: keywords
creator: Jabborov Anvar Mansurjonovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-26
publication date: 2026-03-26
starting page: 34
ending page: 41
doi: 10.62480/tjms.2026.vol54.pp32-39

Reproductive Health Problems in Women
type: item
description: This article provides a scientific analysis of reproductive health problems in women, their causes, risk factors, and impact on overall health. Reproductive health is closely related to a woman’s general wellbeing, and its disorders are manifested through various gynecological conditions, including menstrual cycle disorders, infertility, inflammatory diseases, and hormonal imbalance. The article also highlights the role of social, environmental, and occupational factors in the development of these issues. The study examines preventive measures, modern diagnostic methods, and the importance of a healthy lifestyle in maintaining women’s reproductive health. Based on the findings, practical recommendations have been developed
subject: Articles
  topic: section
subject: reproductive health
  topic: keywords
subject: women’s health
  topic: keywords
subject: gynecological diseases
  topic: keywords
creator: Abdurahimov Bobirjon Abdunabi o‘gli
creator: Rayimova Dilnavoz Olim qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-26
publication date: 2026-03-26
starting page: 31
ending page: 33
doi: 10.62480/tjms.2026.vol54.pp29-31

Analysis of the relationship between hemodynamic parameters and markers of renal dysfunction, Klotho protein, vitamin D, and parathyroid hormone in hypertension
type: item
description: Globally, targeted scientific research is being conducted aimed at a deeper study of the origin and pathogenesis of renal dysfunction (RD), determining the role of Klotho protein in the mechanism of its development. This protein plays an important role in kidney function and the vascular system. A decrease in the amount of Klotho protein intensifies the pathological process in these systems. This study examines the relationship between Klotho protein and RD development.
subject: Articles
  topic: section
subject: Klotho protein
  topic: keywords
subject: HD
  topic: keywords
subject: RD
  topic: keywords
subject: ECG
  topic: keywords
creator: Abdugaffar Gadayev
creator: Matluba Rakhimova
creator: Kamoliddin Sayidov
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-19
publication date: 2026-03-19
starting page: 16
ending page: 21
doi: 10.62480/tjms.2026.vol54.pp16-21

Brain Neuroplasticity in Students Under Conditions of Intensive Learning: Molecular and Cellular Mechanisms
type: item
description: The objective of the present study is to systematize current knowledge regarding the specific molecular, cellular, and systemic mechanisms of neuroplasticity activated in the brains of students during periods of intensive learning, as well as to identify the endogenous and exogenous factors that modulate the efficacy of these processes
subject: Articles
  topic: section
subject: optimizing
  topic: keywords
subject: exogenous
  topic: keywords
subject: endogenous
  topic: keywords
creator: Rashidova Rukhshona Zarifkhonovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-18
publication date: 2026-03-18
starting page: 12
ending page: 15
doi: 10.62480/tjms.2026.vol54.pp12-15

Laparoscopy In The Diagnosis Of Acute Surgical Diseases Of The Abdominal Organs
type: item
description: The article presents an analysis of the results of using diagnostic laparoscopy in 47 patients with suspected acute surgical pathology of the abdominal organs from 2020 to 2025. The author emphasizes the high informative value of the method, which allows for diagnostic verification and determination of treatment tactics with minimal trauma. Particular attention is paid to the diagnosis of acute appendicitis, including the use of the Krieger technique to identify catarrhal forms. The study proves that the implementation of laparoscopy significantly reduces the number of "unjustified" appendectomies and avoids diagnostic errors, the frequency of which reaches 30% with the traditional approach
subject: Articles
  topic: section
subject: Acute surgical pathology
  topic: keywords
subject: diagnostic laparoscopy
  topic: keywords
subject: acute appendicitis
  topic: keywords
creator: Khakimov M.Sh
creator: Jumanazarov A.U.
creator: Ismailova U.A.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-11
publication date: 2026-03-11
starting page: 9
ending page: 11
doi: 10.62480/tjms.2026.vol54.pp9-11

Clinical Efficacy Of Diagnostic Laparoscopy In Abdominal Trauma
type: item
description: The article examines the clinical efficacy of diagnostic laparoscopy in abdominal trauma. Based on the analysis of 129 patients treated at the clinic of Tashkent State Medical University from 2023 to 2025, it was demonstrated that laparoscopy is the most informative minimally invasive method in cases of unclear clinical presentation. The authors developed and substantiated specific indications for this procedure, including the dynamics of pain syndrome, the presence of free fluid detected by ultrasound, and changes in hemodynamic parameters. The use of this technique allows timely identification of internal organ injuries and significantly reduces the number of unnecessary exploratory laparotomies.
subject: Articles
  topic: section
subject: abdominal trauma
  topic: keywords
subject: diagnostic laparoscopy
  topic: keywords
subject: polytrauma
  topic: keywords
subject: hemoperitoneum
  topic: keywords
creator: Khakimov M.Sh
creator: Jumanazarov A.U
creator: Ismailova U.A.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc/4.0
date: 2026-03-08
publication date: 2026-03-08
starting page: 6
ending page: 8
doi: 10.62480/tjms.2026.vol54.pp6-8