Clinical and immunological description of epileptic encephalopathy in early childhood and development of criteria for its early diagnosis

Authors

  • Gulchiroykhon Vafoeva PhD candidate, Tashkent State Medical University
  • Saida Saidkhodjaeva Doctor of Medical Sciences, Associate Professor, Tashkent State Medical University Tashkent, Uzbekistan

DOI:

https://doi.org/10.62480/tjms.2025.vol50.pp74-78

Keywords:

epileptic encephalopathy, seizure, West syndrome

Abstract

This article provides a comprehensive study of the clinical and immunological characteristics of early childhood epileptic encephalopathy. Within the framework of the research, diagnostic criteria were developed to enable early identification of epileptic encephalopathy and its differential diagnosis from other forms of epilepsy. Immunological markers — interleukin-1 (IL-1), interleukin-10 (IL-10), and tumor necrosis factor-alpha (TNF-α) — and their relationship with clinical manifestations were analyzed. Based on the obtained results, scientific and practical recommendations were developed to improve the effectiveness of early diagnosis and treatment.

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Published

2025-11-25

Issue

Section

Articles

How to Cite

Clinical and immunological description of epileptic encephalopathy in early childhood and development of criteria for its early diagnosis. (2025). Texas Journal of Medical Science, 50, 74-78. https://doi.org/10.62480/tjms.2025.vol50.pp74-78