Schenlein-Genoch's Disease In Children: Clinical Characteristics
DOI:
https://doi.org/10.62480/tjms.2025.vol40.pp31-35Keywords:
hemorrhagic vasculitis, Schönlein-Henoch disease, clinical, childrenAbstract
The article retrospectively analyzes the clinical course of hemorrhagic vasculitis in children and the characteristics of the course in children with associated pathologies. Currently, hemorrhagic vasculitis is one of the most common and frequent pathologies in the pediatric population. Its frequency is very variable and depends on the region, its level of economic development, diagnostic and statistical features. Various manifestations of hemorrhagic vasculitis clinical signs, the severity of the course of the disease, the consequences largely depend on the state of the coagulation and anticoagulation systems of hemostasis, and which organ is damaged, and kidney damage determines the probability of a severe course of the disease.
References
Avezova G.S. Changes in the hemostasis system in children with hemorrhagic vasculitis // TTA
newsletter .-2023- №9, p. 223-229. (uzb)
Kudryasheva M.A. Pathogeneticheskie faktori techenia i ikhoda disease Shenleyna-Genoxa u detey//
diss.kand med nauk., Moscow -2015, 176 str. (Russian)
Khramtsova A. S., Yakovleva A. V. Kliniko-epidemiologicheskie osobennosti hemorragicheskogo
vasculita u detey //Molodej-prakticheskomu zdrooochraneniyu. - 2018. - S. 1018-1020(Russian)
Butbul Aviel Y, Dafna L, Pilar G, Brik R. Endothelial function in children with a history of henoch
schonlein purpura // Pediatr Rheumatol Online J. – 2017. - №15(1). – Р. 3-11.
Hahn D, Hodson E.M, Willis N.S, Craig J.C. Interventions for preventing and treating kidney
disease in Henoch-Schönlein Purpura (HSP) // Cochrane Database of Systematic Reviews. – 2015. -
Issue 8. – Р. 74-81.
Jiang MY, Li W, Xu XP, Zhou JQ, Jiang H. Role of p300 in the pathogenesis of Henoch-Schonlein
purpura nephritis and as a new target of glucocorticoid therapy in mice // Chin Med J (Engl). – 2019.
- №132(16). – Р. 1942–1950.
Mir S., Yavascan O., Mutlubas F. et al. Clinical outcome in children with Henoch-Schönlein
nephritis // Pediatr Nephrol. – 2007. – Vol. 22(1). – P.64-70.
Wang X, Zhu Y, Gao L, Wei S, Zhen Y, Ma Q. Henoch-Schönlein purpura with joint involvement:
Analysis of 71 cases // Pediatr Rheumatol Online J. – 2016. - №14(1). – Р. 20-26.
Brogan P., Eleftheriou D., Dillon M. Small vessel vasculitis // Pediatr Nephrol. – 2010. – Vol. 25(6).
– P.1025-35.
Gedalia A. Henoch-Schönlein purpura. Curr Rheumatol Rep // 2004. – Vol. 6(3). – P.195-202.
Bogdanović R. Henoch-Schönlein purpura nephritis in children: risk factors, prevention and
treatment // Acta Paediatr. – 2009. – Vol. 98(12). – P.1882-9.
Chang W.L., Yang Y.H., Wang L.C. et al. Renal manifestations in Henoch-Schönlein purpura: a 10-
year clinical study // Pediatr Nephrol. – 2005. – Vol. 20(9). – P.1269-72.
Chao H.C., Kong M.S., Lin S.J. et al. Gastrointestinal manifestation and outcome of HenochSchonlein purpura in children // Chang Gung Med J. – 2000. – Vol. 23(3). – P.135-41.
Chen S.Y., Kong M.S. Gastrointestinal manifestations and complications of Henoch-Schönlein
purpura // Chang Gung Med J. – 2004. – Vol. 27(3). – P.175-81.
Kawasaki Y., Ono A., Ohara S. et al. Henoch-Schönlein purpura nephritis in childhood:
pathogenesis, prognostic factors and treatment // Fukushima J Med Sci. – 2013. – Vol. 59(1). – P.15-
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