##plugins.themes.academic_pro.article.main##
Abstract
To study the corrective effect of laparoscopic longitudinal gastric resection (LLGR) on obesityrelated metabolic disorders in morbidly obese patients. This scientific work is based on the results of a comprehensive examination and treatment of 187 patients treated for morbid obesity in our clinical bases from 2021 to 2023. Analysis of comorbidities in the compared groups showed that 64% of the comparison groups had metabolic disorders. The majority of these patients were patients with 3rd degree of obesity. Positive changes in lipidogram analysis were observed in patients after LOBR procedure. Also, when hemostasis indicators were studied, convincing positive changes were observed in the 1st and 3rd stages of coagulation hemostasis. In patients with chronic obesity, our recommended modification of LOBR increased cardio esophageal and gastric stapler line strength, eliminating the 2.2% stapler line failure observed in our control group in our main cohort. It also led to a reduction in gastroesophageal reflux disease symptoms from 14% to 6.1%. In conclusion, these pathological changes are closely related to obesity, and the elimination of obesity led to the elimination of these metabolic disturbances
Keywords
metabolic syndrome
morbid obesity
bariatric surgery
concomitant diseases
##plugins.themes.academic_pro.article.details##
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Muradov Alijon Salimovich, Teshaev Oktyabr Ruhullaevich, & Mavlanev Alimbay. (2024). Evaluation of the corrective effect of modified laparoscopic longitudinal gastric resection practice on existing metabolic changes in morbidly obese patients. Texas Journal of Medical Science, 39, 1–7. https://doi.org/10.62480/tjms.2024.vol39.pp1-7
References
- Vermel A.E. Cardiac syndrome X/ Clinical medicine.- 2006. -No. 6. - P. 5-9.
- Kosybaeva A.E., Choudhary S. V. et al. Modern concepts of metabolic syndrome // International
- student scientific bulletin. - 2018. - No. 1.
- Mamedov M.N. Guide to the diagnosis and treatment of metabolic syndrome. - M.: Multiprint, 2005.
- - P. 59-65.
- Metabolic syndrome: modern approaches to diagnosis, prevention, treatment: a teaching aid / A.P.
- Shepelkevich. - Minsk: BSMU, 2007. - 24 p.
- Metabolic syndrome. Tutorial / Yu.P. Uspensky, Yu.V. Petrenko, Z.Kh. Gulunov - St. Petersburg,
- - 60 p.
- Murodov A.S., Teshaev O.R., Mavlyanov O.R. Morbid semizlik bilan origan bemorlar hemostasis
- kursatkichlari buzilislarini yakhshilashda oshkozon bilama resectionsi amaliyotining ahamyati. “New Day in
- Medicine” 2023. 5 (55). S.-80-88
- Murodov A.S., Teshaev O.R., Mavlanev A. Metabolic syndrome - asosiy componentlari va ularni
- bartaraf etish usullari. Problems of biology and medicine 2023, No. 4 (146) 306-310
- Panov AV, Dikalov SI et al. Mitochondria: aging, metabolic syndrome and cardiovascular pathology.
- Formation of a new paradigm. Acta biomedica scientifica. 2020; 5(4): 33-44. doi: 10.29413/ABS.2020-5.4.5
- Roytberg GE, Ushakova TI, Dorosh ZhV The role of insulin resistance in the diagnosis of metabolic
- syndrome // Cardiology. 2004. No. 3. P. 94-101.
- Afshin A., Forouzanfar M.H. et al. Health Effects of Overweight and Obesity in 195 Countries over
- Years. N Engl J Med 2017;377: 13-27.
- Alberti KG, Zimmet PZ, Shaw J. The metabolic syndrome – a new worldwide definition. Lancet.
- ;366:1059 – 1062
- Alijon S. Murodov, Oktyabr R. Teshaev, Аlimbаy Mavlanеv. Corrective effect of longitudinal
- resection of the stomach on concomiented diseases associated with morbid obesity. Central Asian Journal of
- Medicine, 2023#4. 121-132 б
- Alijon S. Murodov., Oktyabr R. Teshaev, Olimboy Mavlyanov. Study of lipid metabolism disorders
- in patients with morbid obesity and evaluation of the corrective effect of laparoscopic sleeve gastrectomy on
- these changes. Tuijin Jishu/Journal of Propulsion Technology ISSN: 1001-4055 Vol. 44 No. 4 (2023)- 6156-
- Balint I.B., Orban L., Farics A., Manfai G., Radics P. (2019) Laparoscopic gastric plication with
- pylorus preserving duodenoileal bypass for treating morbid obesity. Orv Hetil 160(43):1714–1718
- Bays HE, Toth PP et al.. Obesity, adiposity, and dyslipidemia: a consensus statement from the
- National Lipid Association. J Clin Lipidol. 2013;7:304–383.
- Bjornson E, Adiels M, Taskinen MR, Boren J. Kinetics of plasma triglycerides in abdominal obesity.
- Curr Opin Lipidol. 2017;28:11–18. [PubMed].
- Cameron AJ, Magliano DJ, Soderberg S. A systematic review of the impact of including both waist
- and hip circumference in risk models for cardiovascular diseases, diabetes and mortality. Obes Rev.
- ;14:86–94. [PubMed]
- Carrano FM, Peev MP, Saunders JK. et al. (2020) The role of minimally invasive and endoscopic
- technologies in morbid obesity treatment: review and critical appraisal of the current clinical practice. Obes
- Surg 30(2):736– 752.
- Colquitt JL, Pickett K, Loveman E, Frampton GK. Surgery for weight loss in adults. Cochrane
- Database of Systematic Reviews 2014, Issue 8. Art. No.: CD003641. https://doi.org/10.1002/14651 858.
- Cresci B, Cosentino C, Monami M, Mannucci E. Metabolic surgery for the treatment of type 2
- diabetes: a network metaanalysis of randomized controlled trials. Diabetes Obes Metab. 2020 Apr 3.
- https://doi.org/10.1111/dom.14045.
- Dash S, Xiao C, Morgantini C, Lewis GF. New Insights into the Regulation of Chylomicron
- Production. Annu Rev Nutr. 2015;35:265–294. [PubMed]
- Ding L., Fan Y., Li H., Zhang Y. et al. (2020) Comparative efectiveness of bariatric surgeries in
- patients with obesity and type 2 diabetes mellitus: a network metaanalysis of randomized controlled trials.
- Obes Rev 21(8):e13030.
- Ford ES, Giles WH. A comparison of the prevalence of the metabolic syndrome using two
- proposed definitions. Diabetes Care. 2003; 26(3): 575-581. doi: 10.2337/diacare.26.3.575.
- Freedman DM, Ron E, Ballard-Barbash R, et al. Body mass index and all-cause mortality in a
- nationwide US cohort. Int. J. Obes. 2006;30(5):822-829.
- Goitein D., Lederfein D., et al. Mapping of ghrelin gene expression and cell distribution in the
- stomach of morbidly obese patients–a possible guide for efficient sleeve gastrectomy construction Obes
- Surg, 22 (4) (2012), pp. 617-622.
- Grundy SM. Adipose tissue and metabolic syndrome: too much, too little or neither. Eur J Clin
- Invest. 2015;45:1209–1217. [PMC free article] [PubMed].
- Guh DP, Zhang W, Bansback N, et al. The incidence of co-morbidities related to obesity and
- overweight: A systematic review and meta-analysis. BMC Public Health. 2009;9(1). doi: 10.1186/1471-
- -9-88.
- Jensen MD. Role of body fat distribution and the metabolic complications of obesity. J Clin
- Endocrinol Metab. 2008;93:S57–63. [PMC free article] [PubMed].