##plugins.themes.academic_pro.article.main##

Abstract

Chronic obstructive pulmonary disease (COPD) is a serious health problem today. Every year there is an increase in the number of cases of COPD around the world, which is accompanied by a deterioration in the quality of life of patients, temporary loss of ability to work, and even death. Deficiencies of macro- and microelements are currently recognized by world medicine as a global problem. These conditions have a significant impact on the body, presenting an urgent need for the development of effective health strategies to address them. According to available data, nutritional deficiencies are quite common in patients with COPD. Numerous studies highlight the impact of micronutrient deficiencies on disease progression. Currently, the connection between bronchopulmonary diseases and low levels of vitamin D and magnesium in the body of patients is being actively studied. Insufficient outdoor activity, infrequent exposure to sunlight, poor diet, alcoholism, smoking, decreased ability of the skin to synthesize vitamin D in smokers, general exhaustion of the body, and the use of certain antibiotics can be the causes of low levels of vitamin D and magnesium. Many studies indicate that deficiencies of these elements may be associated with decreased lung function and increased exacerbations in COPD, which contributes to disease progression. Deficiency conditions, which often remain undiagnosed, can negatively affect the prognosis of the disease. This study identifies the incidence of low blood levels of vitamin D and magnesium and demonstrates the relationship between low levels of these elements and the severity of COPD

Keywords

COPD vitamin D magnesium frequency of occurrence

##plugins.themes.academic_pro.article.details##

How to Cite
Fattakhova Yuliya Edgarovna, & Matrzayeva Shoira Gulimboyevna. (2024). Micronutrient Level Among Patients with Chronic Obstructive Pulmonary Disease. Texas Journal of Medical Science, 32, 78–83. https://doi.org/10.62480/tjms.2024.vol32.pp78-83

References

  1. Аверина И. А., Сергиенко Д. Ф., Дугугиева О. С., Гаджиев Р. М. Хронические заболевания легких в контексте иммуногенетического влияния витамина D // Успехи современной науки. ‒ 2017. ‒ Т. 24, No 4. ‒ С. 209-218.
  2. Ахметова А. А. Полиморфизм FOKI, TAGI, BSMI, APAI и CDX2 рецептора витамина D (VDR) с восприимчивостью к туберкулезу легких: сравнительный анализ // Вестник КГМА им. И. К. Ахунбаева. ‒ 2018. ‒ No 4. ‒ С. 17-23.
  3. Гладкевич А. В. и др. Роль магния в патогенезе депрессивных расстройств, некоторых коморбидных заболеваний и способы их коррекции //Журнал Гродненского государственного медицинского университета. – 2015. – №. 4 (52). – С. 15-25
  4. Громова О. А., Торшин И. Ю., Мартынов А. И. Роль обеспеченности витамином Д в регуляции иммунитета и в обеспечении противоинфекционной защиты у взрослых // Терапия. ‒ 2017. ‒ No 6 (16). ‒ С. 81-88
  5. Громова О. А., Торшин И. Ю., Томилова И. К., Гилельс А. В. Метаболиты витамина D: роль в диагностике и терапии витамин D-зависимой патологии // Практическая медицина. ‒ 2017. ‒ No 5 (106). ‒ С. 4-10.,
  6. Иванцова Н. Л., Белякова А. Г., Дмитриевская М. И. Обоснование использования витамина Д у больных ХОБЛ с целью коррекции иммунологических показателей // Таврический медико-биологический вестник. – 2014. ‒ Т. 17, No 4. ‒ С. 29-31
  7. Купаев В. И., Нурдина М. С., Лимарева Л. В. Дефицит витамина D как фактор риска неконтролируемого течения бронхиальной астмы // Пульмонология. ‒ 2017. ‒ Т. 27, No 5. ‒ С. 624-628
  8. Altura, B. M. Role of brain [Mg2+] in alcohol-induced hemorrhagic stroke in a rat model: a 31P-NMR in vivo study / B. M. Altura [et al.] // Alcohol. - 1995. - No 12. - P. 131-136
  9. Aziz H. S. et al. Serum magnesium levels and acute exacerbation of chronic obstructive pulmonary disease: a retrospective study //Annals of Clinical & Laboratory Science. – 2005. – Т. 35. – №. 4. – С. 423-427.
  10. Burkes RM, Ceppe AS, Doerschuk CM, et al. Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort – 2020 – Т. 157 – С. 856-865.
  11. Ferrari R. et al. The relationship between Vitamin D status and exacerbation in COPD patients–a literature review //Respiratory Medicine. – 2018. – Т. 139. – С. 34-38
  12. Forli L. et al. Vitamin D deficiency, bone mineral density and weight in patients with advanced pulmonary disease //Journal of internal medicine. – 2004. – Т. 256. – №. 1. – С. 56-62.
  13. Garcia-Aymerich J. et al. Lung function impairment, COPD hospitalisations and subsequent mortality //Thorax. – 2011. – Т. 66. – №. 7. – С. 585-590.
  14. Janssens W. et al. Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene //Thorax. – 2010. – Т. 65. – №. 3. – С. 215-220.
  15. Jorde I. et al. Association of serum vitamin D levels with disease severity, systemic inflammation, prior lung function loss and exacerbations in a cohort of patients with chronic obstructive pulmonary disease (COPD) //Journal of Thoracic Disease. – 2021. – Т. 13. – №. 6. – С. 3597
  16. Kunisaki K. M., Niewoehner D. E., Connett J. E. Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study //American journal of respiratory and critical care medicine. – 2012. – Т. 185. – №. 3. – С. 286-290.
  17. Makarevich А. E. Effects of vitamin D3 in obstructive lung diseases (review) // Практикуючий лiкар. ‒ 2017. ‒ Т. 6. - № 1. ‒ С. 21-31
  18. Malinovschi A. et al. Severe vitamin D deficiency is associated with frequent exacerbations and hospitalization in COPD patients //Respiratory research. – 2014. – Т. 15. – С. 1-8.
  19. Martineau A. R. et al. Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial //The lancet Respiratory medicine. – 2015. – Т. 3. – №. 2. – С. 120-130.
  20. McKeever T. M. et al. A multivariate analysis of serum nutrient levels and lung function //Respiratory research. – 2008. – Т. 9. – С. 1-10.
  21. Mekov E. et al. Vitamin D deficiency and insufficiency in hospitalized COPD patients //PLoS One. – 2015. – Т. 10. – №. 6. – С. e0129080
  22. Postnikova L. B. et al. Significance of biochemical parameters of saliva in the diagnosis of chronic obstructive pulmonary disease at exacerbation //Klinicheskaia Laboratornaia Diagnostika. – 2004. – №. 10. – С. 16-18.
  23. Ruljančić N. et al. COPD: magnesium in the plasma and polymorphonuclear cells of patients during a stable phase //COPD: Journal of Chronic Obstructive Pulmonary Disease. – 2007. – Т. 4. – №. 1. – С. 41-47.
  24. Song W. J., Chang Y. S. Magnesium sulfate for acute asthma in adults: a systematic literature review //Asia Pacific Allergy. – 2012. – Т. 2. – №. 1. – С. 76-85.
  25. Zhu B. et al. Vitamin D deficiency is associated with the severity of COPD: a systematic review and meta-analysis //International journal of chronic obstructive pulmonary disease. – 2015. – С. 1907-1916
  26. Zhu M. et al. The association between vitamin D and COPD risk, severity, and exacerbation: an updated systematic review and meta-analysis //International journal of chronic obstructive pulmonary disease. – 2016. – С. 2597-2607.

Most read articles by the same author(s)