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Abstract

Heterocyclic compounds, owing to their diverse applications including pharmaceuticals and industrial use, hold a prominent position within organic chemistry. This study focused on the synthesis and characterization of Schiff base compounds as a subset of heterocyclic molecules. Compound [N1] was synthesized by condensing 3,4 Diamino benzoic acid and 4-Dimethyl amino benzaldehyde, followed by subsequent reactions to yield compounds [N2], [N3], [N4], and [N5]. Each compound was characterized through Fourier-transform infrared spectroscopy (FTIR). The FTIR spectra exhibited distinctive absorption bands signifying various functional groups within each compound. The spectra confirmed the presence of key bonds such as OH, C=O, C=N, C-H, and S-H within the compounds. This thorough characterization validated the successful synthesis of the Schiff base compounds and facilitated their structural analysis. The study underscores the importance of precise characterization in elucidating the structure and composition of novel compounds, contributing to the broader understanding of their potential applications.

Keywords

Heterocyclic Derivatives Synthesis Schiff Base Compounds Fourier-Transform Infrared Spectroscopy (FTIR)

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How to Cite
Zena Ayad Noori, Tabarak Ali Hussein Mahdi, Walid Khaled Obaid, Rusul Abather Mohsen, Safaa Kamel Abdul Razzaq Ali, & Russul Jaleel Hassan. (2023). Synthesis and Biological Evolution of Some Heterocyclic Derivatives. Texas Journal of Medical Science, 23, 75–79. https://doi.org/10.62480/tjms.2023.vol23.pp75-79

References

  1. M. S. Al-Rawi, H. A. Hassan, D. F. Hassan and R. M. Abdulla, International Journal for Sciences and Technology, 8, 48(2013).
  2. A.K. Singh, G. Mishra and K. Jyoti, Journal of Applied pharmaceutical science, 44-49(2011).
  3. A.Achson, An introduction to the chemistry of heterocyclic compound 3rd ed., Willy- Intersciences, India (2009).
  4. Schiff, H. (Mittheilungen aus dem Universitätslaboratorium in Pisa: eine neue Reihe organischer Basen), Justus Liebigs Annalen Der Chemie, 131: 118–119 (1864).
  5. Kadhum, M. (Synthesis, Identification and Study of Some New Schiff Bases as Inhibitors for Brass Corrosion and Bacterial Growth), J. of Basrah Res. ((Sci.)), 37(2):89-115(2011).
  6. Schiff, H. (Giornale di scienze naturalied economiche(in Italian)), Palermo, II: 1– 59(1867).
  7. Al-Dhalimy, A. M. (2021). Effects of ocimum tenuiflorum on induced testicular degeneration by filgrastim in Wistar rats. Archives of Razi Institute, 76(5), 1555.‏
  8. Al-Hasan, B. A., Alhatami, A. O., Abdulwahab, H. M., Bustani, G. S., Hameed, M. A., & Jawad, A. H. (2022). First report of Avian metapneumovirus type B in Iraqi broiler flocks with swollen head syndrome. Veterinary World, 15(1), 16.‏
  9. Gati, M. A., & Bustani, G. S. (2022). The Effect of Vitamin C Pretreatment on Acute Nickel Nephrotoxicity in Male Mice. Revista Electronica de Veterinaria, 130-138.‏
  10. A'laa Hassan Abdul Hussain, D., Al Haideri, H., AL-Zaidi, A. A., Abadi, A. K., Bustani, G. S., & Al-Dhalimy, A. M. B. (2022). Ameliorative Effect of The Moringa Pterygosperma Extract Against Cyclophosphamide on the Reproductive System. Revista Electronica de Veterinaria, 77-84.‏
  11. Bustani, G. S., Jabbar, M. K., AL-Baghdady, H. A. F., & Al-Dhalimy, A. M. B. (2022, January). Protective effects of curcumin on testicular and sperm parameters abnormalities induced by nicotine in male rats. In AIP Conference Proceedings (Vol. 2386, No. 1). AIP Publishing.‏