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Abstract

Chronic gastroduodenitis (CGD) in the structure of diseases of the digestive organs belong to the most common pathology of childhood with progressive growth exceeding 100 cases per 1000 children. For comparison, according to A.B. Mazurin in 1989, the prevalence of this pathology was recorded at the level of 79 cases per 1000 children under the age of 14. In addition to a distinct upward trend in detectable HCG, which averages 10% per year, there is a tendency to aggravate the course not only due to an increase in the specific gravity of erosive, subatrophic and atrophic forms, but also due to polymorbid flow with the presence of up to 2 or more concomitant diseases. As the most frequent comorbid conditions of HCG, a number of authors indicate violations of the trophological status (dyslipidemia, changes in the musculoskeletal and cardiovascular systems, a high frequency of autonomic dysfunctions, dysbiotic disorders. The presence of frequent concomitant changes on the part of other organs and systems in children with HCG raises the question of the existence of uniform pathogenetic mechanisms in which HCG is considered as a pathological process involving an integral organism with a violation of metabolic processes, homeostatic parameters, regulatory circuit, intestinal endoecology, and, accordingly, the optimality of the development of a growing organism. Such a complex of changes leads to a decrease in the adaptive capabilities of the child's body with subsequent changes in behavioral reactions and social relations, which goes beyond the scope of gastroenterological pathology proper

Keywords

gastroduodenoscopy Helicobacter pylori children clinic

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How to Cite
Khudayberganova N.Kh, Rakhmatullayeva G.K, & Tagaeva M. Kh. (2023). Modern Ideas About the Formation of Helicobacter Pylori Associated Gastroduodenal Pathology in Children. Texas Journal of Multidisciplinary Studies, 18, 30–38. Retrieved from https://zienjournals.com/index.php/tjm/article/view/3548

References

  1. Akimova VP, Kokurkin GV. Neurovegetative disorders in children with chronic gastroduodenitis. Bulletin of the Chuvash University. 2009; 2:316-7. Russian.
  2. Vorobyova AV. About the problem of treatment of chronic gastroduodenitis in children // Bulletin of New Medical Technologies (Electronic edition). 2013 [quoted December 20, 2013]; 1: [about 6 pages]. Russian. Available at: http://www. medtsu.tula.ru/VNMT/Bulletin/E2013-1/4670.pdf .
  3. Gurova M.M., Uspensky Yu.P. Features of vegetative regulation in adolescent children with chronic gastroduodenitis, depending on the stage of the disease. Kuban Scientific Medical Bulletin. 2010; 8:122. Russian.
  4. Gurova MM, Tsirkunova BB. Concomitant diseases of the digestive system in adolescent children with chronic gastroduodenitis. Bulletin of the Novgorod State University. 2014; 78:37-43. Russian.
  5. Drobysheva OV, Botvinyev OK. Functional state of cardiac and pyloric sphincters, Oddi sphincter in children with undifferentiated connective tissue dysplasia and in the absence of dysplasia. Russian Journal of Gastroenterology, Hepatology and Coloproctology. 2009;19(5):39-43. Russian.
  6. Zaprudnov A.M., Grigoriev K.I., Filin V.A., Safonov A.B., etc. Achievements of domestic gastroenterology: origins, current state, prospects. Pediatrics. 2008;87(6):8-13. Russian.
  7. Kotovsky A.V., Sirotkin E.A. Forecasting the nature of the course of duodenal ulcer and chronic gastroduodenitis in children. Saratov Scientific and Medical Journal. 2008;3(21):84-7. Russian.
  8. Ledyaev M.Yu., Stepanova O.V., Shakhova N.V. Syndrome of autonomic dysfunctions in children: myths and reality. The attending physician. 2009; 1:27-9. Russian.
  9. Sapozhnikov VG, Vorobyova AV. Objective criteria of chronic digestive diseases in children. Bulletin of New Medical Technologies (Electronic edition). 2015 [cit. January 28, 2015]; tula.ru/VNMT/Bulletin/E2015-1/5062.pdf . DOI: 10.12737/7593.
  10. Sapozhnikov VG, Dobrodeeva LC, Beyuzerov VP. Immunocorrective therapy in children with helicobacter-associated diseases. Russian Pediatric Journal. 1998; 2:66-7. Russian
  11. Sapozhnikov V.G., Kuklina N.A., Shcheplyagina L.L. The clinical significance of studying risk factors in the helicobacterpositive form of chronic gastroduodenitis in children. Russian Pediatric Journal. 1998; 6:25-9. Russian.
  12. Sapozhnikov V.G., Sapozhnikov S.V. Treatment of helicobacter-associated gastroduodenitis in children. Bulletin of New Medical Technologies (Electronic edition). 2013 [quoted on December 2, 2013]; 1: [about 4 pages]. Russian. Available at: http://www. medtsu.tula.ru/VNMT/Bulletin/2013-1/4570.pdf .
  13. Sapozhnikov V.G., Sapozhnikov L.G., Zablodsky A.P. On pyloric helicobacteriosis in children. Pediatrics. 1993; 4:61-4. Russian.
  14. Sapozhnikov V.G., Kuklina P.A. On the etiopathogenetic role of pyloric helicobacteriosis in the development of gastrointestinal tract diseases in children. Pediatricians
  15. Sapozhnikov VG. Modern methods of diagnosis and treatment of gastroduodenal pathology in children. Arkhangelsk, 1997. Rus.
  16. Sapozhnikov VG. Helicobacterioassociated gastroduodenitis in children. Medical newspaper. 2014; 42:9. Russian.
  17. Sapozhnikov VG. Chronic inflammatory diseases of the gastroduodenal zone in children. Arkhangelsk, 1995. Rus.
  18. Sapozhnikov VG. Echography of the stomach and duodenum in children. Bulletin of New Medical Technologies (Electronic edition). 2013 [quoted on October 23, 2013]; 1: [about 6 pages]. Russian. Available at: http://medtsu.tula.ru/VNMT/Bulletin/E2013-1/4596.pdf .
  19. Sichinava I., Gorelov I., Shershevskaya A. Pathomorphosis of chronic gastroduodenitis in children for 6 years after antihelicobacter treatment. Doctor. 2011; 8:11-4. Russian.
  20. Baskerville A, Newell D. Naturally occurring chronic gastritis and Campylobacter pylori infection in rhesus monkeys: a potential model of gastritis in humans. The gut. 1988;29(4):465-72.
  21. Laine L., Sukhauer L., Franz J. and co-author. Low frequency of occurrence of Helicibacter pylori resistant to clarithromycin on the background of amoxicillin therapy. Alimony. Pharmacol. ter. 1998;12(9):887-92.
  22. Soares F., Rocha A., Rocha S. et al. Differences in the phenotypes of peripheral blood lymphocytes in Helicobacter pylori-positive children and adults with duodenal ulcer. wedge. microbiol. Infect. 2007;13(11):1083-8.
  23. Kasim A., Sebastian S., Thornton O. et al. Eradication therapy of Helicobacter pylori based on rifabutin and furazolidone after unsuccessful attempts of standard eradication of the first and second line in patients with dyspepsia. Alimony. Pharmacol. ter. 2005;21(1)