Clinical Pharmacological Approach To Rational Drug Treatment Of Chronic Heart Failure
DOI:
https://doi.org/10.62480/tjms.2025.vol42.pp45-47Keywords:
Chronic heart failure, rational pharmacotherapy, clinical pharmacologyAbstract
The clinical pharmacological approach to the rational drug treatment of chronic heart failure (CHF) focuses on optimizing therapeutic strategies to improve patient outcomes. This article examines the pharmacological classes of drugs used in CHF management, including angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, diuretics, aldosterone antagonists, and novel agents. The mechanisms of action, indications, contraindications, and potential adverse effects of these drugs are analyzed. Special emphasis is placed on the importance of individualized treatment, drug interactions, and evidence-based guidelines. Advances in pharmacotherapy and personalized medicine approaches for enhancing the efficacy and safety of CHF treatment are also discussed.
References
Alyavi A.L., Kamilova U.K., Rasulova D.Z. Diagnosis and treatment of chronic heart failure.
Tashkent 2016. P.196.
Cardiology in diagrams and tables, translation from English. M., 2013.
Kukes V.G. Clinical pharmacology. M., 2018. 936 b.
Larina V.N., Skiba I.K., Skiba A.S. Brief review of updates to clinical guidelines for chronic heart
failure of the European Society of Cardiology 2021. Russian Journal of Cardiology
;27(2):4820:97-105. doi:10.15829/ 1560-4071-2022-482.
Saidova Sh.A., Yakubov A.V., Pulatova N.I. “Clinical pharmacology of cardiotonic drugs” 2017.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
User Rights
Under the Creative Commons Attribution-NonCommercial 4.0 International (CC-BY-NC), the author (s) and users are free to share (copy, distribute and transmit the contribution).
Rights of Authors
Authors retain the following rights:
1. Copyright and other proprietary rights relating to the article, such as patent rights,
2. the right to use the substance of the article in future works, including lectures and books,
3. the right to reproduce the article for own purposes, provided the copies are not offered for sale,
4. the right to self-archive the article.









