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Abstract
The levels of antibodies to insulin analysed in 58 children with diabetes mellitus with the help of enzyme immunoassay were found to be increasing with the disease duration and insulin dependence in the patients. The concentration of antibodies was found correlating with the frequency of viral infections in the anamnestic data of the children, and with the presence of microangiopathic, lipodystrophic and immunopathologic conditions
Keywords
children
insulin
diabetes mellitus
antibodies
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Shermatov Rasuljon Mamasiddikovich, Sodikova Shakhlo Rakhmanovna, & Axunbekova Odina Mahmudjanovna. (2025). Antibodies To Insulin In Children With Diabetes Mellitus. Texas Journal of Medical Science, 41, 12–15. Retrieved from https://zienjournals.com/index.php/tjms/article/view/5970
References
- Baturin V. A., Bykov Yu. V., Mamtseva G. I., Uglova T. A., Yagudina R. I. Determination of the level
- of antibodies to the melatonin receptor 1a in children with type 1 diabetes mellitus at different stages
- of the disease. Medical Bulletin of the North Caucasus. 2018; 13(4):671-673. DOI –
- https://doi.org/10.14300/mnnc.2018.13133.
- Akhmedov G.A. The importance of autoantibodies in insulin-dependent diabetes mellitus. // Kazan
- Medical Journal, 2017, Vol. 98, No. 4. P. 519-521.
- Petryaikina E.E., Laptev D.N., Vorontsova I.G., Demidov N.A., Ryapolova Yu.A. Type 1 diabetes
- mellitus in children and adolescents of Moscow. Data from the Moscow segment of the Federal
- Register of Patients with Diabetes Mellitus 2015–2020 // Problems of Endocrinology. - 2021. - Vol.
- - No. 6. - P. 113-123. doi: https://doi.org/10.14341/probl12795.
- Poletaev, A. B. Antibodies to insulin receptors as biomarkers – precursors of type 2 diabetes mellitus
- / A. B. Poletaev // All-Russian interdisciplinary journal. TERRA MEDICА. – 2013. – No. 1. – P. 22–
- Peterkova V.A., Shestakova M.V., Bezlepkina O.B., i dr. Sakharnyi diabet 1 tipa u detei // Sakharnyi
- diabet. - 2020. - T. 23. - №1S. - S. 4-40. doi: https://doi.org/ 10.14341/DM12504 [DOI] [Google
- Scholar]
- IDF DIABETES ATLAS 9-th edition 2019. Chapter 3. Global picture. Diabetes incidence and
- prevalence in children and adolescents. Available from: https://diabetesatlas.org/en/
- Mayorov Alexander Y., Vikulova Olga K., Zheleznyakova Anna V., Isakov Mikhail А., Melnikova
- Olga G., Kononenko Irina V., Shestakova Marina V., Dedov Ivan I.. Epidemiology of acute diabetes complications (coma) according to the Federal Diabetes register of the Russian Federation (2013–
- Diabetes mellitus. 2019 Feb;21(6):444–454. doi: 10.14341/dm10028. [DOI] [Google Scholar]
- Lipatov DV, Vikulova OK, Zheleznyakova AV, et al. Trends in the epidemiology of diabetic
- retinopathy in Russian Federation according to the Federal Diabetes Register (2013–2016). Diabetes
- mellitus. 2018;21(4):230-240. doi: https://doi.org/ 10.14341/DM9797 [DOI]
- Galstyan Gagik R., Vikulova Olga K., Isakov Michail A., Zheleznyakova Anna V., Serkov Alexey A.,
- Egorova Daria N., Artemova Ekaterina V., Shestakova Marina V., Dedov Ivan I.. Trends in the
- epidemiology of diabetic foot and lower limb amputations in Russian Federation according to the
- Federal Diabetes Register (2013–2016) Diabetes mellitus. 2018 Aug;21(3):170–177. doi:
- 14341/dm9688. [DOI] [Google Scholar]
- Shamkhalova Minara S., Vikulova Olga K., Zheleznyakova Anna V., Isakov Michail A., Shestakova
- Marina V., Dedov Ivan I.. Trends in the epidemiology of chronic kidney disease in Russian Federation
- according to the Federal Diabetes Register (2013–2016) Diabetes mellitus. 2018 Aug;21(3):160–169.
- doi: 10.14341/dm9687. [DOI] [Google Scholar]
- Dedov Ivan I., Shestakova Marina V., Peterkova Valentina A., Vikulova Olga K., Zheleznyakova Anna
- V., Isakov Mikhail А., Laptev Dmitry N., Andrianova Ekaterina A., Shiryaeva Tatyana Y.. Diabetes
- mellitus in children and adolescents according to the Federal diabetes registry in the Russian
- Federation: dynamics of major epidemiological characteristics for 2013–2016. Diabetes mellitus. 2018
- Feb;20(6):392–402. doi: 10.14341/dm9460. [DOI] [Google Scholar]
- Dedov Ivan I., Shestakova Marina V., Vikulova Olga K., Zheleznyakova Anna V., Isakov Michail А..
- Diabetes mellitus in Russian Federation: prevalence, morbidity, mortality, parameters of glycaemic
- control and structure of glucose lowering therapy according to the Federal Diabetes Register, status
- Diabetes mellitus. 2018 Aug;21(3):144–159. doi: 10.14341/dm9686. [DOI] [Google Scholar]
- Dedov Ivan I., Shestakova Marina V., Peterkova Valentina A., Vikulova Olga K., Zheleznyakova Anna
- V., Isakov Mikhail А., Laptev Dmitry N., Andrianova Ekaterina A., Shiryaeva Tatyana Y.. Diabetes
- mellitus in children and adolescents according to the Federal diabetes registry in the Russian
- Federation: dynamics of major epidemiological characteristics for 2013–2016. Diabetes mellitus. 2018
- Feb;20(6):392–402. doi: 10.14341/dm9460. [DOI] [Google Scholar]
- Titovich, E. V. HLA haplotypes, autoantibodies to (β-cells): role in predicting type 1 diabetes mellitus
- (results of 11-year observation) / E. V. Titovich, T. L. Kuraeva, S. A. Prokofiev [et al.] // Diabetes
- mellitus. - 2014. - No. 4. - P. 12-17.
- El-Ziny, М. A. Epidemiology of childhood type 1 diabetes mellitus in Nile Delta, northern Egypt – a
- retrospective study / M. A. El-Ziny, N. A. Salem, A. K. El-Hawary [et al.] // J. Clin. Res. Pediatr.
- Endocrinol. – 2014. – Vol. 6. – P. 9–15.
- Wherrett, D. K. Trials in the prevention of type 1 diabetes: current and future / D. K. Wherrett // Can.
- J. Diabetes. – 2014. – Vol. 38. – P. 279–284.
- Ziegler, A. G. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in
- children / A. G. Ziegler, M. Rewers, O. Simell [et al.] // JAMA. – 2013. – Vol. 309. – P. 2473–2479.