##plugins.themes.academic_pro.article.main##
Abstract
The study of the statement of the hemostatic system and vascular endothelium was made in newborns with hypoxic lesions of the nervous system. Some indicators of hemostasis (PTT, APTT, TT and fibrinogen) were determined in cord blood, as well as endothelial dysfunction marker Endothelin-1. In newborns who underwent a chronic hypoxia, a statistically significant increase of the fibrinogen level and endothelin-1 were revealed in the umbilical cord blood. During hypoxic lesions of the nervous system in newborns the vascular endothelium primarily reacts, causing activation of hemostasis and cerebral blood flow disorders.
Keywords
cerebral hypoxia
hemostasis
vascular endothelium
endothelin
##plugins.themes.academic_pro.article.details##
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Dilmuradova K.R, & Ziyadullayeva H.O. (2023). Study of the relationship between hemostasis and vascular endothelium in hypoxic lesions of the nervous system in newborns. Texas Journal of Medical Science, 22, 24–26. https://doi.org/10.62480/tjms.2023.vol22.pp24-26
References
- Bryksina E.Yu. Pathogenetic aspects of hypoxic-ischemic encephalopathy in newborns UDC 616.8-092+616.831-008.6:616.053-32.
- Barashnev Yu.I., Rozanov A.V., et al. The role of hypoxic traumatic brain injuries in the formation of childhood disability. Ros. Bulletin of Perinatology and Pediatrics 2006; 4:41-46.
- Volodin N.N. Principles of management of newborns with respiratory distress syndrome: method, recommended / Volodin N.N.-M., 1998-15 p
- Dilmuradova K.R. and Ziyadullaeva H.O., The state of the hemostasis system and vascular endothelium in perinatal lesions of the nervous system. Problems of Biology and Medicine.2022. No. 5(139).-p.315-322.
- Ivanov D.O.. Indicators of the hemostasis system in children with severe perinatal pathology: http//www.medlinks.ru/article.php.sid=22090
- Kovalev VV // Medical technologies in the protection of women's reproductive health. - Nizhnevartovsk 2003, - p. 139-142,
- Mikhalev E.V. Ontogenetic features of hemostasis in newborns. Mikhalev E.V., Filippov G.P., S.P. Ermolenko // Anesthesiology and resuscitation. 2003.-№1.-S.28-30.
- Horinouchi T., Terada K.//Jornal of Pharmacological Sciences.123,2,2013, 85-101.