Multicomponent Photocomposition as A Source for Development New Anti-Inflammatory Medicines

Authors

  • Khakimov Z.Z Tashkent Medical Academy
  • Babazhanov A.U Urgench branch of the Tashkent Medical Academy
  • Rakhmanov A.Kh Uzbek Research Chemical-Pharmaceutical Institute named after A. Sultanov
  • Tursunova L.I Uzbek Research Chemical-Pharmaceutical Institute named after A. Sultanov
  • Khadzhieva U.A the Republic of Uzbekistan

DOI:

https://doi.org/10.62480/tjms.2023.vol20.pp29-32

Keywords:

aseptic arthritis, phytocomposition, medicinal plants

Abstract

The results of experimental studies on mature white male rats showed that phytocompositions 1, 2 and 3 containing various extracts of medicinal plants have a distinct antiphlogogenic activity. Among the studied phytocollections, composition 3 showed a higher anti-inflammatory activity compared to other studied phytocollections. The studied new mixtures of medicinal plants have a higher antiphlogogenic activity than canephron, especially phytocomposition 3, and in terms of their pharmacological activity, it is not inferior to the gold standard non-steroidal anti-inflammatory drug - sodium diclofenac.

References

Mitrofanova I.S., Stolbova M.V., Ovchinnikova Yu.G., Morina A.A. Adverse drug reactions//National Association of Scientists (NAU). -2017. -Vol. 31, No. 4. -S.19-21.

Naumova E.M., Valentinov B.G., Khadartseva K.A. Some aspects of drug therapy in the elderly // Bulletin of new medical technologies. Electronic edition. -2019. -#2. -p.95-101.

Kareva E.N., Oleinikova O.M., Serebrova S.Yu. et al. Side effects of non-steroidal anti-inflammatory drugs and ways of their prevention// Experimental and clinical pharmacology. -2022. -Volume 85, No. 3. -p.33-44.

Kutyakov V.A., Shadrina L.B., Trufanova L.V. et al. Nonsteroidal anti-inflammatory drugs: key mechanisms of action and neuroprotective potential// Experimental and clinical pharmacology. -2019. -Volume 82, No. 2. -p.38-46.

Prokhorovich E.A. Non-steroidal anti-inflammatory drugs - a collection of clones or a community of bright individuals? The view of a clinical pharmacologist//Russian Medical Journal. -2020. -#6. -S.2-9.

Samylina I.A., Sorokina A.A., Pyatigorskaya N.V. Medicinal herbal preparations//Pharmatheca for practitioners. -2010. -#10. -p.80-82.

Kaysina E.A., Marchenko N.M., Smirnova G.I. Phytotherapy in medical practice // Electronic collection of articles based on the material of the Annual Educational Conference with International Participation "Modern Trends in the Development of Health Saving Technologies". -2022. - P.54-57.

Khakimov Z. Z., Rakhmanov A. Kh., Khadzhieva U. A., Tursunova L. I. Antiexudative Activity of a New Phytocomposition Consisting from the Flora of Central Asia. //American Journal of Medicine and Medical Sciences. - 2023.- Vol. .13, N 2.-R.39-42.

Makushkina Yu.E. Pharmacotherapeutic efficacy of the herbal remedy "Arkositel" in ischemic kidney damage// Abstract of the dissertation for the degree of Candidate of Medical Sciences. Ulan-Ude-2013. -21s.

Ivanova E.A., Voronina T.A. Effect of diclofenac sodium on the level of histamine and serotonin in acute exudative inflammation in rats//Pharmacokinetics and pharmacodynamics. -2018. -#2. -p.12-15.

Khakimov Z.Z., Rakhmanov A.Kh., Mavlanov Sh.R. Anti-inflammatory activity of a mixture of medicinal plants. LLC "TIBBIYOT NASHRIOTI MATBAA UYI", Tashkent. -2022.- 228 p.

Khakimov Z.Z., Rakhmanov A.Kh. MavlanovSh.R., Abduvaliev A.A., Allaeva M.D. Investigation of influence of medicinal collection containing flavonoids on the course of histamine induced inflammation//Scientific journal “Fundamentalis scientiam”-2018.-No.21.-R.45-47.

Djanaev, G. Yu, and M. A. Mamadjanova. "Effect on the Organism When Chronic Administration of a New Phytopreparation." Scholastic: Journal of Natural and Medical Education 2.4 (2023): 188-195.

Khakimov Z. Z. Effect of Derivatives of Glycyrrhetic Acid on the Intensity of Free Radical Processes During Immobilization Stress //Pioneer: Journal of Advanced Research and Scientific Progress. – 2022. – Т. 1. – №. 1. – С. 7-12.

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Published

2023-05-08

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Articles

How to Cite

Multicomponent Photocomposition as A Source for Development New Anti-Inflammatory Medicines. (2023). Texas Journal of Medical Science, 20, 29-32. https://doi.org/10.62480/tjms.2023.vol20.pp29-32