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Abstract
The current study aimed to evaluate some immune variables in COVID-19 patients for chronic and acute conditions, as the study included the collection of (120) blood samples for individualssuspected of having respiratory distress syndrome and of both sexes and a age ranging from 29 years to 60 years for a period from 15/12/2021 to 20/7/2022 from a hospital Nineveh AlAhly and Ibn Sina Governmental Hospital. The samples recorded in the study after the confirmation of the diagnosis of COVID-19 were divided into two groups, the first groupincluded (25) patients withchronic respiratory distress syndrome who are in the intensive care unit and need Ventilator support, the second group included (25) patients who suffer from moderate symptoms and the control sample included (25) blood samples for healthy individuals. Through the study, some immune variables of the study sample were evaluated, which included the total numbers of white blood cells, the absolute numbers of neutrophil, lymphatic, mononucleus, acidophilic cells.
Keywords
white
healthy
collection
samples
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Zaid Duraid Idrees Al-Hamdani, Rojan G. AL-Allaff, & Bashar Sadeq Noomi. (2023). Study the variation in blood cell counts in patients with moderate to severe COVID-19 infection. Texas Journal of Medical Science, 19, 58–64. https://doi.org/10.62480/tjms.2023.vol19.pp58-64
References
- Follow-up of the effect of variation in immunological measures after recovery from infection with the Corona virus, especially in patients with chronic conditions.
- Perform a lymphoblast transformation test to see how T cells respond to slicators such as Phytohaemagglutinin.
- Estimation of CD4+/CD8+ in COVID-19 patients , especially patients with chronic conditions.
- Nanotechnology Perceptions. 8 (1): 7–16.
- References
- Sasmita Poudel Adhikari, Sha Meng, Yu-Ju Wu et al., “Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review,” Infectious Diseases of Poverty, vol. 9, no. 1, p. 29, 2020.
- Roman Wölfel, Victor M. Corman, Wolfgang Guggemos, Michael Seilmaier et al., “Virological assessment of hospitalized patients with COVID-2019,” Nature, vol. 581, no. 7809, pp. 465–469, 2020.
- Fei Zhou , Ting Yu , Ronghui Du , Guohui Fan et al., “Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study,” The Lancet, vol. 395, no. 10229, pp. 1054–1062, 2020.
- Luciano Gattinoni, Davide Chiumello, Pietro Caironi, Mattia Busana, et al., “COVID-19 pneumonia: different respiratory treatments for different phenotypes?” Intensive Care Medicine, vol. 46, no. 6, pp. 1099–1102, 2020.
- Stefano Aliberti, Grazia Messinesi, Silvia Gamberini, Sveva Maggiolini et al., “Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases,” BMC Pulmonary Medicine, vol. 14, no. 1, pp. 1–8, 2014.
- Chuan Qin, Luoqi Zhou, Ziwei Hu, Shuoqi Zhang et al., “Dysregulation of immune response in patients with Coronavirus 2019 (COVID-19) in Wuhan, China,” Clinical Infectious Diseases, vol. 53, no. 9, pp. 1–30, 2020.
- Zsuzsanna Varga, Andreas J Flammer, Peter Steiger, Martina Haberecker et al., “Endothelial cell infection and endotheliitis in COVID-19,” The Lancet, vol. 395, no. 10234, pp. 1417-1418, 2020.
- Aneta Manda, Michał P. Pruchniak, Magdalena Araźna, and Urszula A. Demkow, “Neutrophil extracellular traps in physiology and pathology,” Central European Journal of Immunology, vol. 1, no. 1, pp. 116–121, 2014.
- Qin, C., Zhou, L., Hu, Z., Zhang, S., Yang, S., Tao, Y., Xie, C., Ma, K., Shang, K., Wang, W. and Tian, D.S., 2020. Dysregulation of immune response in patients with coronavirus 2019 (COVID-19) in Wuhan, China. Clinical infectious diseases, 71(15), pp.762-768.
- Fan, Yi؛ Zhao؛ Shi؛ Zhou، "Bat Coronaviruses in China"، Viruses، 11 (3): 210، doi:10.3390/v11030210، ISSN 1999-4915،
- Salih, R.A., Taha, A.A. and Mohamed, N.S., 2022. Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with COVID-19. Journal of Applied Sciences and Nanotechnology, 2(2), pp.112-123.
- Elderdery, A.Y., Elkhalifa, A.M., Alsrhani, A., Zawbaee, K.I., Alsurayea, S.M., Escandarani, F.K., Alhamidi, A.H., Idris, H.M., Abbas, A.M., Shalabi, M.G. and Mills, J., 2022. Complete Blood Count Alterations of COVID-19 Patients in Riyadh, Kingdom of Saudi Arabia. Journal of Nanomaterials, 2022.
- Parackova, Z., Bloomfield, M., Klocperk, A. and Sediva, A., 2021. Neutrophils mediate Th17 promotion in COVID‐19 patients. Journal of leukocyte biology, 109(1), pp.73-76.
- Zuo, Y., Yalavarthi, S., Shi, H., Gockman, K., Zuo, M., Madison, J.A., Blair, C., Weber, A., Barnes, B.J., Egeblad, M. and Woods, R.J., 2020. Neutrophil extracellular traps in COVID-19. JCI insight, 5(11).
- Zhang J.J., Cao Y.Y., Tan G., Dong X., Wang B.C., Lin J., Yan Y.Q.,Liu G.H., Akdis M., and Akdis C.A. (2020) Clinical, radiological andlaboratory characteristics and risk factors for severity and mortality of289 hospitalized COVID-19 patients. Allergy. Citation by Li, andXiaoming. (2020) "Predictive values of neutrophil-to-lymphocyte ratio on disease severity and mortality in COVID-19 patients: a systematic review and meta-analysis." Critical Care 24.1 1-10
- Yang X., Yu Y., Xu J., Shu H., Liu H., Wu Y., and Shang Y. (2020). Clinical course and outcomes of critically ill patients with SARS‐CoV‐2 pneumonia in Wuhan, China: A single‐centered, retrospective, observational study. The Lancet Respiratory Medicine. 8(5), 475–481. 10.1016/s2213-2600(20)30079-5. Citation by Fathi, Nazanin, and Nima Rezaei. (2020) "Lymphopenia in COVID‐19: Therapeutic opportunities." Cell biology international 44.9 1792-1797.
- Zheng M., Gao Y., Wang G., Song G., Liu S., Sun D., and Tian Z.-
- (2020) Functional exhaustion of antiviral lymphocytes in COVID‐19patients. Cellular & Molecular Immunology, 17(5), 533–535.10.1038/s41423-020-0402-2.
- Ruan Q., Yang K., Wang W., Jiang L., and Song J. (2020) Clinicalpredictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. Springer Berlin Heidelberg.
- Diao B., Wang C., Tan Y., Chen X., Liu Y., Ning L., and Chen Y.(2020). Reduction and functional exhaustion of T cells in patients withcoronavirus disease 2019. Frontiers in Immunology. 11, 827. Citation by Fathi, Nazanin, and Nima Rezaei. (2020) "Lymphopenia in COVID‐19: Therapeutic opportunities." Cell biology international. 44.9 1792-1797.
- Cortés-Vieyra, R., Gutiérrez-Castellanos, S., Álvarez-Aguilar, C., Baizabal-Aguirre, V.M., Nuñez-Anita, R.E., Rocha-López, A.G. and Gómez-García, A., 2021. Behavior of eosinophil counts in recovered and deceased COVID-19 patients over the course of the disease. Viruses, 13(9), p.1675.
- Pozdnyakova, O., Connell, N.T., Battinelli, E.M., Connors, J.M., Fell, G. and Kim, A.S., 2021. Clinical significance of CBC and WBC morphology in the diagnosis and clinical course of COVID-19 infection. American journal of clinical pathology, 155(3), pp.364-375.
- Zhu, B., Feng, X., Jiang, C., Mi, S., Yang, L., Zhao, Z., Zhang, Y. and Zhang, L., 2021. Correlation between white blood cell count at admission and mortality in COVID-19 patients: a retrospective study. BMC Infectious Diseases, 21(1), pp.1-5.
- Soedarsono, S., Yunita, D., Ayu Lirani, E., Kartika Sari, R., Indrawan Pratama, Y., Listiati, A. and Supriyanto, B., 2022. The role of simple blood tests and a modified chest X-ray scoring system in assessing the severity disease and mortality risk in COVID-19 patients in a secondary hospital, Indonesia. International Journal of General Medicine, pp.5891-5900.
- Zhang, F., Gan, R., Zhen, Z., Hu, X., Li, X., Zhou, F., Liu, Y., Chen, C., Xie, S., Zhang, B. and Wu, X., 2020. Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals. Signal transduction and targeted therapy, 5(1), pp.1-11.